ID   S35B3_CAEBR             Reviewed;         363 AA.
AC   Q61LC0; A8X824;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Adenosine 3'-phospho 5'-phosphosulfate transporter 2;
DE   AltName: Full=Adenosine 3'-phosphate 5'-phosphosulfate transporter;
DE   AltName: Full=PAPS transporter 2;
DE   AltName: Full=Solute carrier family 35 member B3 homolog;
GN   Name=pst-2; ORFNames=CBG08992;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Mediates the transport of adenosine 3'-phospho 5'-
CC       phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal
CC       sulfuryl donor for sulfation events that take place in the Golgi (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35B
CC       subfamily. {ECO:0000305}.
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DR   EMBL; HE601284; CAP28785.3; -; Genomic_DNA.
DR   RefSeq; XP_002641140.1; XM_002641094.1.
DR   AlphaFoldDB; Q61LC0; -.
DR   SMR; Q61LC0; -.
DR   STRING; 6238.CBG08992; -.
DR   PRIDE; Q61LC0; -.
DR   EnsemblMetazoa; CBG08992.1; CBG08992.1; WBGene00030668.
DR   GeneID; 8583133; -.
DR   KEGG; cbr:CBG_08992; -.
DR   CTD; 8583133; -.
DR   WormBase; CBG08992; CBP08146; WBGene00030668; Cbr-pst-2.
DR   eggNOG; KOG1582; Eukaryota.
DR   HOGENOM; CLU_036019_2_0_1; -.
DR   InParanoid; Q61LC0; -.
DR   OMA; QFGYYIG; -.
DR   OrthoDB; 1116466at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0046964; F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR013657; UAA.
DR   PANTHER; PTHR10778; PTHR10778; 1.
DR   Pfam; PF08449; UAA; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..363
FT                   /note="Adenosine 3'-phospho 5'-phosphosulfate transporter
FT                   2"
FT                   /id="PRO_0000213382"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        310..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   363 AA;  40552 MW;  661D3FEE1EE4F9F4 CRC64;
     MTVAQIHSDC SSSMLPRHIK DDVEPIHLLG FNIARKPKWL QFVLLSGAIF ILYLGYGYMQ
     ELIFKLPGMK PFGWTLTLIQ FVIYSGCGYA ECAVWHNTKR MIPWRIYGVI AFFTVATMGL
     SNASVGYLNY PTQVIFKCCK LIPVLIGGIL IQGKRYGWID ISAAILMSLG IIMFTLADNK
     VSPNFDSRGY IMISGALLAD AVIGNIQEKN MKKYGGSSNE VVLYSYGIGS VFIFTYVVLS
     GEIFSAIPFF LENSWKTFGY ALIFSFLGYL GVNVVLTHIK VFGALVAVTV TTLRKALTII
     LSFLLFSKPF TIEYVYAGSV VMLAIYLNLY SKNKASWDHM IRIFVARAMG YHAVATKKDP
     MMV