ID   S35E3_BOVIN             Reviewed;         313 AA.
AC   A4IFK2;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Solute carrier family 35 member E3;
GN   Name=SLC35E3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TPT transporter family. SLC35E subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC134617; AAI34618.1; -; mRNA.
DR   RefSeq; NP_001077123.1; NM_001083654.1.
DR   AlphaFoldDB; A4IFK2; -.
DR   SMR; A4IFK2; -.
DR   STRING; 9913.ENSBTAP00000042665; -.
DR   PaxDb; A4IFK2; -.
DR   PRIDE; A4IFK2; -.
DR   Ensembl; ENSBTAT00000045262; ENSBTAP00000042665; ENSBTAG00000031919.
DR   GeneID; 509009; -.
DR   KEGG; bta:509009; -.
DR   CTD; 55508; -.
DR   VEuPathDB; HostDB:ENSBTAG00000031919; -.
DR   VGNC; VGNC:34831; SLC35E3.
DR   eggNOG; KOG1441; Eukaryota.
DR   GeneTree; ENSGT00730000111164; -.
DR   HOGENOM; CLU_048347_3_2_1; -.
DR   InParanoid; A4IFK2; -.
DR   OMA; QGLGMLC; -.
DR   OrthoDB; 938634at2759; -.
DR   TreeFam; TF329429; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000031919; Expressed in oocyte and 105 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR   GO; GO:0005338; F:nucleotide-sugar transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR004853; Sugar_P_trans_dom.
DR   Pfam; PF03151; TPT; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..313
FT                   /note="Solute carrier family 35 member E3"
FT                   /id="PRO_0000297898"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   313 AA;  34766 MW;  51F32423FC37DF67 CRC64;
     MASLADRVRG NGRIAAGLLL NLLVSICIVF LNKWIYVHYG FPNMSLTLVH FVVTWLGLYV
     CQKLDIFAPK SLPPSKLLLL ALSFCGFVVF TNLSLQNNTI GTYQLAKAMT TPVIIVIQTL
     CYKKTFSTKI RLTLIPITLG VILNSYYDVK FNFLGTVFAA LGVLVTSLYQ VWVGAKQHEL
     QVNSMQLLYY QAPMSSAMLL VAVPFFEPVF AEGGIFGPWS VSALLMVLLS GVIAFMVNLS
     IYWIIGNTSP VTYNMFGHFK FCITLFGGYV LFKDPLSINQ GLGMLCTLFG ILAYTHFKLS
     EQEGSKSKLV QRP