S35F1_MOUSE
ID S35F1_MOUSE Reviewed; 408 AA.
AC Q8BGK5; Q3TNT3; Q8BKD4; Q8BVI2; Q8BX52;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Solute carrier family 35 member F1;
GN Name=Slc35f1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RC TISSUE=Brain cortex, Cerebellum, Embryonic spinal ganglion, Eye,
RC Hypothalamus, and Olfactory bulb;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- FUNCTION: Putative solute transporter. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SLC35F solute transporter family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC37158.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA.; Evidence={ECO:0000305};
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DR EMBL; AK038601; BAC30061.1; -; mRNA.
DR EMBL; AK048957; BAC33499.1; -; mRNA.
DR EMBL; AK053426; BAC35383.1; -; mRNA.
DR EMBL; AK053545; BAC35422.1; -; mRNA.
DR EMBL; AK078169; BAC37158.1; ALT_SEQ; mRNA.
DR EMBL; AK083768; BAC39016.1; -; mRNA.
DR EMBL; AK139331; BAE23959.1; -; mRNA.
DR EMBL; AK165021; BAE38004.1; -; mRNA.
DR EMBL; BC059075; AAH59075.1; -; mRNA.
DR CCDS; CCDS23843.1; -.
DR RefSeq; NP_848790.2; NM_178675.4.
DR AlphaFoldDB; Q8BGK5; -.
DR SMR; Q8BGK5; -.
DR STRING; 10090.ENSMUSP00000101113; -.
DR iPTMnet; Q8BGK5; -.
DR PhosphoSitePlus; Q8BGK5; -.
DR MaxQB; Q8BGK5; -.
DR PaxDb; Q8BGK5; -.
DR PeptideAtlas; Q8BGK5; -.
DR PRIDE; Q8BGK5; -.
DR ProteomicsDB; 256678; -.
DR Antibodypedia; 19478; 31 antibodies from 14 providers.
DR DNASU; 215085; -.
DR Ensembl; ENSMUST00000105473; ENSMUSP00000101113; ENSMUSG00000038602.
DR GeneID; 215085; -.
DR KEGG; mmu:215085; -.
DR UCSC; uc007fbk.2; mouse.
DR CTD; 222553; -.
DR MGI; MGI:2139810; Slc35f1.
DR VEuPathDB; HostDB:ENSMUSG00000038602; -.
DR eggNOG; KOG2766; Eukaryota.
DR GeneTree; ENSGT00390000015655; -.
DR HOGENOM; CLU_039639_0_0_1; -.
DR InParanoid; Q8BGK5; -.
DR OMA; VYIGLIC; -.
DR OrthoDB; 659967at2759; -.
DR PhylomeDB; Q8BGK5; -.
DR TreeFam; TF313645; -.
DR BioGRID-ORCS; 215085; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Slc35f1; mouse.
DR PRO; PR:Q8BGK5; -.
DR Proteomes; UP000000589; Chromosome 10.
DR RNAct; Q8BGK5; protein.
DR Bgee; ENSMUSG00000038602; Expressed in humerus cartilage element and 155 other tissues.
DR Genevisible; Q8BGK5; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR009262; SLC35_F1/F2/F6.
DR Pfam; PF06027; SLC35F; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..408
FT /note="Solute carrier family 35 member F1"
FT /id="PRO_0000307308"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 3
FT /note="P -> S (in Ref. 1; BAC33499)"
FT /evidence="ECO:0000305"
FT CONFLICT 112
FT /note="L -> Q (in Ref. 1; BAE38004)"
FT /evidence="ECO:0000305"
FT CONFLICT 326
FT /note="C -> F (in Ref. 1; BAC35422)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 408 AA; 45304 MW; 8E9669BC21CF6C55 CRC64;
MIPPEPPQPQ LQPPPPPAPP NHVVTTIENL PAEGSGGVSL SASSRASMRQ RIRKVLNREM
LISVALGQVL SLLVCGIGLT SKYLAEDFHA NTPVFQSFLN YILLFLVYTT TLAVRQGEEN
LLAILRRRWW KYMILGLIDL EANYLVVKAY QYTTLTSVQL LDCFVIPVVI LLSWFFLLIR
YKAVHFIGIV VCILGMGCMV GADVLVGRHQ GAGENKLVGD LLVLGGATLY GISNVWEESI
IRTLSRVEFL GMIGLFGAFF SGIQLAIMEH KELLKVPWDW QIGLLYVGFS ACMFGLYSFM
PVVIKKTSAT SVNLSLLTAD LYSLFCGLFL FHYKFSGLYL LSFFTILIGL VLYSSTSTYI
AQDPRVYKQF RNPSGPVVDL PSTAQVEPSV TYTSLGQETE EEPHVRVA
