S35G3_MOUSE
ID S35G3_MOUSE Reviewed; 340 AA.
AC Q5F297; O35281;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 2.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Solute carrier family 35 member G3;
DE AltName: Full=Acyl-malonyl-condensing enzyme 1;
GN Name=Slc35g3; Synonyms=Amac1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX PubMed=9056918; DOI=10.1042/bst025020s;
RA Kells A.P., Maynard P.V.;
RT "RT-PCR of fatty acid elongases.";
RL Biochem. Soc. Trans. 25:20S-20S(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SLC35G solute transporter family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD11967.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AAD26636.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAD26636.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=CAI51954.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF016712; AAD11967.1; ALT_SEQ; mRNA.
DR EMBL; AF111715; AAD26636.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL603707; CAI51954.1; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; Q5F297; -.
DR SMR; Q5F297; -.
DR STRING; 10090.ENSMUSP00000099646; -.
DR TCDB; 2.A.7.28.3; the drug/metabolite transporter (dmt) superfamily.
DR PhosphoSitePlus; Q5F297; -.
DR PaxDb; Q5F297; -.
DR PRIDE; Q5F297; -.
DR Ensembl; ENSMUST00000102586; ENSMUSP00000099646; ENSMUSG00000018776.
DR MGI; MGI:1927128; Slc35g3.
DR VEuPathDB; HostDB:ENSMUSG00000018776; -.
DR eggNOG; ENOG502RCFC; Eukaryota.
DR GeneTree; ENSGT00940000153249; -.
DR InParanoid; Q5F297; -.
DR OMA; VTPFDIM; -.
DR PRO; PR:Q5F297; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q5F297; protein.
DR Bgee; ENSMUSG00000018776; Expressed in spermatid and 7 other tissues.
DR ExpressionAtlas; Q5F297; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..340
FT /note="Solute carrier family 35 member G3"
FT /id="PRO_0000269559"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 51..176
FT /note="EamA 1"
FT DOMAIN 274..327
FT /note="EamA 2"
FT REGION 11..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 340 AA; 35573 MW; 439A9A66389162EB CRC64;
MAASHPYFNL PDFTQPSPPS TPASLPSKHH HRCGPSNATK GLFVALLGGG LSAGFVGPFS
RMAYQTSQLP SLELLIFRCL FHLPIALLLK FRGDPLLGPP DVRVRAFLHA ILNVLSIGCA
YSAVQVVPAG NAVTVRKGSS TVCSALLALC LESQGLSGYA WCGLFGSTLG LIIIVGPGLG
TLQEGTTGLY TALGYVLAFL GGLALSLGLQ IYRSLHFPSC LPTVAFLFGL VGLMVSVPGL
FVLQTPVLPQ DTLSWSCVVA VGLLALVSFV CVSYAVTKAH PALVCAVLHS EVVVALMLQY
YVLYETVAPS DIMGAGVVLG SIAIITAQNL SCDKEGQTEE
