S35G3_PANPA
ID S35G3_PANPA Reviewed; 338 AA.
AC Q0Q7V0;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Solute carrier family 35 member G3;
DE AltName: Full=Acyl-malonyl-condensing enzyme 1;
DE AltName: Full=Transmembrane protein 21A;
GN Name=SLC35G3; Synonyms=AMAC1, TMEM21A;
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=17101974; DOI=10.1073/pnas.0603224103;
RA Xing J., Wang H., Belancio V.P., Cordaux R., Deininger P.L., Batzer M.A.;
RT "Emergence of primate genes by retrotransposon-mediated sequence
RT transduction.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:17608-17613(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- MISCELLANEOUS: The gene encoding this protein appears to have arisen by
CC SVA-mediated retrotransposition of the SLC35G6 gene in the primate
CC lineage.
CC -!- SIMILARITY: Belongs to the SLC35G solute transporter family.
CC {ECO:0000305}.
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DR EMBL; DQ482900; ABE68914.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0Q7V0; -.
DR SMR; Q0Q7V0; -.
DR Proteomes; UP000240080; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR Pfam; PF00892; EamA; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..338
FT /note="Solute carrier family 35 member G3"
FT /id="PRO_0000269554"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 49..174
FT /note="EamA 1"
FT DOMAIN 272..325
FT /note="EamA 2"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 338 AA; 35283 MW; A433DD4075C59BF2 CRC64;
MAGSHPYFNQ PDSTHPSPPS APPSLHWYQR CQPSDATSGL LVALLGGGLP AGFVGPLSRM
AYQASNLPSL ELLIWRCLFH LPIALLLKLR GDPLLGPPDI RSRAFFCALL NILSIGCAYS
AVQVVPAGNA ATVRKGSSTV CSAVLTLCLE SQGLSGYDWC GLLGCILGLI IIVGPGLWTL
QEGTTGVYTA LGYAEAFLGG RALSLGLLVY RSLHFPSCLP TVAFLSGLVG LLGSVPGLFV
LQTPVLPSDL LSWSCVGAVG ILALVSFTCV GYAVTKAHPA LVCAVLHSEV VVALILQYYM
LHETVAPSDI MGAGVALGSI AIITARNLSC ERTGKVEE