ABCGK_DICDI
ID ABCGK_DICDI Reviewed; 730 AA.
AC Q8T674; Q55GF4;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=ABC transporter G family member 20;
DE AltName: Full=ABC transporter ABCG.20;
GN Name=abcG20; ORFNames=DDB_G0267430;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND NOMENCLATURE.
RC STRAIN=AX4;
RX PubMed=12456012; DOI=10.1128/ec.1.4.643-652.2002;
RA Anjard C., Loomis W.F.;
RT "Evolutionary analyses of ABC transporters of Dictyostelium discoideum.";
RL Eukaryot. Cell 1:643-652(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; AF482397; AAL91504.1; -; Genomic_DNA.
DR EMBL; AAFI02000003; EAL73167.1; -; Genomic_DNA.
DR RefSeq; XP_647230.1; XM_642138.1.
DR AlphaFoldDB; Q8T674; -.
DR STRING; 44689.DDB0191238; -.
DR PaxDb; Q8T674; -.
DR PRIDE; Q8T674; -.
DR EnsemblProtists; EAL73167; EAL73167; DDB_G0267430.
DR GeneID; 8616035; -.
DR KEGG; ddi:DDB_G0267430; -.
DR dictyBase; DDB_G0267430; abcG20.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_014367_1_0_1; -.
DR InParanoid; Q8T674; -.
DR OMA; FTENFTD; -.
DR PhylomeDB; Q8T674; -.
DR PRO; PR:Q8T674; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IGC:dictyBase.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IGC:dictyBase.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000412; ABC_2_transport.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR PRINTS; PR00164; ABC2TRNSPORT.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51012; ABC_TM2; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..730
FT /note="ABC transporter G family member 20"
FT /id="PRO_0000346860"
FT TRANSMEM 520..540
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 572..592
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 602..622
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 634..654
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 692..712
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 15..244
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 489..717
FT /note="ABC transmembrane type-2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
FT REGION 281..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 47..54
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 730 AA; 81025 MW; F3E354832E2E75BA CRC64;
MSNSNNNNNN KKLAISLKNV CRGYGNTKVI DNLNLQIKSG TINCLIGASG SGKTTILRTI
LGRLIPDSGE VLVFGKRPHD IGGVPGSICG FCPQEGALYY DLTLDHTLNF FSNVHQIPKD
KFESKKNEII KLLDLPQINS RSVGLLSGGQ KKRVSLAVAL LHSPKLLILD EPTVGIDMEV
ASNIWSYLRS LANSGVTIII TTHYINEAVG SDNVFLLRDG KILENGAPNY LIERYESQTL
EEVFLKLCKR DNAQSIVDSK KNNNNSYFSS QEIIDVESHI VNNNNNNNNN NNNNNYNNND
DEENYNDDIY NDKKPLIGIS KEDENNTNGS TNKESGILFR FYKVLLHSVA IGKRKFIQII
RNKVVLSFEL LSPSVQVLLY FLAIGGSPKN LEFGVVNLDV GPIGSMYINS LSNTGIFNFH
NYNSTTEAIE QIKSGNSFGL LDINAQFSEA ILENFMNLSQ YNPNGQIDLY MDFTNYQITL
IVEQQLALSF ETLAKQQANI TMNPIKTVTP TVYGNPNSKF IDFLAPGMVC LISFAHAISI
TSVSFVKEKV DGSLDRLFAY GVRTSSIVFG HFLGHLPLLL VQITVLLLIA IYGFNVPIEG
NIALVFLMTV SLAFVGMSLG LVISAVSRVE TEAIQLSLGV YFPTLICSGT LWPLQSLPNW
FVWFPNILPA THAGNAMRDI MLKGVGLHYK EVWVAFLVVL SWLIFLIFIA VLALNEKDKN
LKLSCFKKRK
