ID   S38A7_DANRE             Reviewed;         465 AA.
AC   Q6DEL1; Q498Q4;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 7;
DE   AltName: Full=Solute carrier family 38 member 7;
GN   Name=slc38a7; ORFNames=zgc:100802;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB; TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative sodium-dependent amino acid/proton antiporter.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       {ECO:0000305}.
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DR   EMBL; BC100117; AAI00118.1; -; mRNA.
DR   EMBL; BC077100; AAH77100.1; -; mRNA.
DR   RefSeq; NP_001003648.1; NM_001003648.1.
DR   AlphaFoldDB; Q6DEL1; -.
DR   SMR; Q6DEL1; -.
DR   STRING; 7955.ENSDARP00000068329; -.
DR   PaxDb; Q6DEL1; -.
DR   PRIDE; Q6DEL1; -.
DR   GeneID; 445254; -.
DR   KEGG; dre:445254; -.
DR   CTD; 55238; -.
DR   ZFIN; ZDB-GENE-040801-266; slc38a7.
DR   eggNOG; KOG1305; Eukaryota.
DR   InParanoid; Q6DEL1; -.
DR   PhylomeDB; Q6DEL1; -.
DR   PRO; PR:Q6DEL1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015180; F:L-alanine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015182; F:L-asparagine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015183; F:L-aspartate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005290; F:L-histidine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015190; F:L-leucine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015191; F:L-methionine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015194; F:L-serine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid transport; Ion transport; Membrane; Reference proteome; Sodium;
KW   Sodium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..465
FT                   /note="Putative sodium-coupled neutral amino acid
FT                   transporter 7"
FT                   /id="PRO_0000319601"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        111
FT                   /note="S -> T (in Ref. 1; AAI00118)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   465 AA;  50678 MW;  0DC200BFC3DEB82C CRC64;
     MSRPDRAINS EAGDWGYSED AGERAWLLQS PSVDSVQPPS QSDDSRGGTS SLGAVFIVVN
     AALGAGLLNF PAAFNMAGGI TAGVTLQMCM MAFIITGLVI LAYCSQVSNE STYQEVVRAV
     CGKALGVICE LAIAVYTFGT CIAFLIIIGD QLDKLIGAIN NESEKEISLH WYTDRKFTIT
     LTSVLIILPL SIPKEIGFQK YASTLSVIGT WYVTIIVIVK YIWPSKDVSP GIIPVRPASW
     TDVFNAMPTI CFGFQCHVSS VPVFNSMKKP EIRPWWGVVT ISMIICLFVY TGTGVCGFLS
     FGSSVSQDVL MSYPSDDVAV AIARAFIIIC VVTSYPILHF CGRAVLEGLW LRFKGEEVET
     DVAKERRRRI LQTLVWFCLT LILALFIPDI GRVISLIGGL AACFIFVFPG LCLIQAKLSE
     HDVRSNSWNA MVAYGVIMVT IGAFIFGQTT TNAIYKDIIN NPNSP