ID   S38A7_PONAB             Reviewed;         462 AA.
AC   Q5R9F5;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 7;
DE   AltName: Full=Solute carrier family 38 member 7;
GN   Name=SLC38A7; Synonyms=SNAT7;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates sodium-dependent transport of amino acids,
CC       preferentially L-glutamine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}. Note=In neurons, located in soma and axons.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       {ECO:0000305}.
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DR   EMBL; CR859433; CAH91605.1; -; mRNA.
DR   RefSeq; NP_001125946.1; NM_001132474.1.
DR   AlphaFoldDB; Q5R9F5; -.
DR   SMR; Q5R9F5; -.
DR   STRING; 9601.ENSPPYP00000008376; -.
DR   GeneID; 100172881; -.
DR   KEGG; pon:100172881; -.
DR   CTD; 55238; -.
DR   eggNOG; KOG1305; Eukaryota.
DR   InParanoid; Q5R9F5; -.
DR   OrthoDB; 697331at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0030424; C:axon; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043025; C:neuronal cell body; ISS:UniProtKB.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; ISS:UniProtKB.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid transport; Ion transport; Membrane; Phosphoprotein;
KW   Reference proteome; Sodium; Sodium transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..462
FT                   /note="Putative sodium-coupled neutral amino acid
FT                   transporter 7"
FT                   /id="PRO_0000319599"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         28
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NVC3"
SQ   SEQUENCE   462 AA;  49882 MW;  58E3F1D2C76E9006 CRC64;
     MAQVSINNDY SEWGLSTDAG ERARLLQSPC VDTAPKSEWE ASPGGPDRGT TSTLGAIFIV
     VNACLGAGLL NFPAAFSTAG GVAAGIALQM GMLVFIISGL VILAYCSQAS NERTYQEVVW
     AVCGKLTGVL CEVAIAVYTF GTCIAFLIII GDQQDKIIAV MAKEPEGASG PWYTDRKFTI
     SLTAFLFILP LSIPREIGFQ KYASFLSVVG TWYVTAIVII KYIWPDKEMT PGNILTRPAS
     WMAVFNAMPT ICFGFQCHVS SVPVFNSMQQ PEVKTWGGVV TAAMVIALAV YMGTGICGFL
     TFGAAVDPDV LLSYPSEDMA VAVARAFIIL SVLTSYPILH FCGRAVVEGL WLRYQGVSVE
     EDVGRERRRR VLQTLVWFLL TLLLALFIPD IGKVISVIGG LAACFIFVFP GLCLIQAKLS
     EMEEVKPASW WVLVSYGVLL VTLGAFIFGQ TTANAIFVDL LA