ID   S38AA_PONAB             Reviewed;        1121 AA.
AC   Q5RC98;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 10;
DE   AltName: Full=Solute carrier family 38 member 10;
GN   Name=SLC38A10;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative sodium-dependent amino acid/proton antiporter.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       {ECO:0000305}.
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DR   EMBL; CR858381; CAH90609.1; -; mRNA.
DR   RefSeq; NP_001125330.1; NM_001131858.1.
DR   AlphaFoldDB; Q5RC98; -.
DR   SMR; Q5RC98; -.
DR   GeneID; 100172229; -.
DR   KEGG; pon:100172229; -.
DR   CTD; 124565; -.
DR   InParanoid; Q5RC98; -.
DR   OrthoDB; 1109791at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid transport; Ion transport; Membrane; Phosphoprotein;
KW   Reference proteome; Sodium; Sodium transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..1121
FT                   /note="Putative sodium-coupled neutral amino acid
FT                   transporter 10"
FT                   /id="PRO_0000318977"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          434..691
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          731..904
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          965..1068
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        437..458
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..479
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..526
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..557
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        731..750
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        980..1020
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1037..1068
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         612
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5I012"
FT   MOD_RES         772
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HBR0"
FT   MOD_RES         802
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HBR0"
FT   MOD_RES         890
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:E9PT23"
FT   MOD_RES         966
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HBR0"
FT   MOD_RES         999
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9HBR0"
SQ   SEQUENCE   1121 AA;  120388 MW;  3E62D646AE2BDE3C CRC64;
     MTAAAASNWG LITNIVNSIV GVSVLTMPFC FKQCGIVLGA LLLVFCSWMT HQSCMFLVKS
     ASLSKRRTYA GLAFHAYGKA GKMLVETSMI GLMLGTCIAF YVVIGDLGSN FFARLFGFQV
     GGTFRMFLLF AVSLCIVLPL SLQRNMMASI QSFSAMALLF YTVFMFVIVL SSLKHGLFSG
     QWLRRVSYVR WEGVFRCIPI FGMSFACQSQ VLPTYDSLDE PSVKTMSSIF ASSLNVVTTF
     YVMVGFFGYV SFTEATAGNV LMHFPSNLVT EMLRVGFMMS VAVGFPMMIL PCRQALSTLL
     CEQQQKDGTF AAGGYMPPLR FKALTLSVVF GTMVGGILIP NVETILGLTG ATMGSLICFI
     CPALIYKKIH KNALSSQVVL WVGLGILVVS TVTTLSVSED VPEDLAEEAP GGRLGEAEGL
     MKVEAARLSA QDPVVAVAED GREKPKLPKE REELEQAQIK GPVDVPGRED GKEAQEEAQL
     DRPGQGIAVP VGEAHRHEPP VPHDKVVVDE GQDQEVPEEN KPPSRHAGRK APGVQGQMAP
     PLPDSEREKR EPEQGEVGKR PGQAQALEEA GDLPEDPQKV PEADGQPAVQ PAKEDLEPGD
     GGLHPRPQAV LSEQQNGLAV DEGEKAEGVP PPGNAAGDTG QPAEDSDHGG KPPLPEEKPA
     PGAGLPPEPR EQRDVERAGG DQAASQLEEA GRAEMLDHAV LLQVIKEQQV QQKRLLDQQE
     KLLAVIEEQH KEIHQQRQED EEDKPRQVEV HPEPGAAVPR GQEAPEGKAR ETMENLPPLP
     LDPVLRAPGG RPAPSQDLNQ RSLEHPERPV GRDPAGPPDG GPDTEPRAAQ AKPRDGQKDA
     APGAAGTVKE LLKGLEQVPV PDPAREAGGP EERLAEEFPG QSQDVTGGGS QDRKKPGKEV
     AATGTGILKE ANWLVAGPGA EMGDPHMKPK QMSRDLGLAV DLPGGAEGAA AQPQAVLRQP
     ELRVISDGEQ GGQQGHRLDH GGYLEMRKEA RGGDHMPVSH EQLGGEEDAA VPEPRQRPEP
     ELGLKQAVPG GQRPDNAKPN RDLKLQAGSD LRRRRRDLGP HAEGELAPRD RVIIGLNPLP
     DVQVNDLRGA LDAQLRQAAG GALQVVHSRQ LRQAPGAPEE S