ID   S38AA_XENLA             Reviewed;        1045 AA.
AC   Q6PCF9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 10;
DE   AltName: Full=Solute carrier family 38 member 10;
GN   Name=slc38a10;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative sodium-dependent amino acid/proton antiporter.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC059341; AAH59341.1; -; mRNA.
DR   RefSeq; NP_001080033.1; NM_001086564.1.
DR   AlphaFoldDB; Q6PCF9; -.
DR   SMR; Q6PCF9; -.
DR   PRIDE; Q6PCF9; -.
DR   DNASU; 379725; -.
DR   GeneID; 379725; -.
DR   KEGG; xla:379725; -.
DR   CTD; 379725; -.
DR   Xenbase; XB-GENE-958200; slc38a10.S.
DR   OrthoDB; 1109791at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 379725; Expressed in zone of skin and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid transport; Ion transport; Membrane; Reference proteome; Sodium;
KW   Sodium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1045
FT                   /note="Putative sodium-coupled neutral amino acid
FT                   transporter 10"
FT                   /id="PRO_0000318978"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          412..584
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        412..477
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..547
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..576
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        625..658
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1045 AA;  116690 MW;  25026D6C1F93A1F7 CRC64;
     MAASNWGLIM NIVNSIVGVS VLTMPFCFQQ CGILLGTLLL MLCTWMAHHS CMFLVKSASV
     SKRRTYAGLA FHAYGKVGKM MVETSMIGLM LGTCIAFYVV IGDLGSSFFA RLFGLEVSEG
     FRVFLLFSVS LCIVLPLSLQ RNMMAFIQSF SAMALMFYTV FMFVIVLSSF KHGLFSGQWL
     KHVSYIRWEG VFRCIPIYGM SFACQSQVLP TYDSLDDPSV KIMSSIFALS LNVVTTFYIT
     VGFFGYVSFP ETIAGNVLVN FPSNLVTEMI RVGFMMSVAV GFPMMILPCR QALNTLLFEQ
     QQKDGTFTAG GYMPPLRFKI LTLVVVFGTM LGGILIPNVE TILGLTGATM GSLICLICPA
     LIYKKIHKKG LASQFILGVG LLILVISTYT TLTVTEEPTQ IKSELLERID LKEEKDPEQI
     NSQKSDEKAK VEQPGDNRDK PKLPPKNPEE EQIKGPIEGP QKEKDTKKQE EVQLDRPDQG
     DIAVPVGEAH RHEPPIPQDE VAVDEKKDQG EREEKKESVV DINSTEKKDK QQINLEKEPE
     IKDQAEANKG INEPVPQKPP QEVNDPNKQQ LVNPPTPRLK EQPPFKDLEG IIKDLAVPVE
     IKKNAEIAEE KDNNDFANPV KAIENPPIKD EKNEQIPGDP GKESHVEPKA EDNQAEAGKA
     ELLDHAFLLQ VIKEQQVQQK RLLDQQEKLL EVIKEQHMEI HQQKGDEDQQ DKLEGNIADK
     NKEELKAEAR VAQKPLEGDK LENVGEVNAK VDKPAVEEHV VVVEKEQNPA LNQVVKGNVP
     DVKKNDHKIE APKINVEEVK VPISAGKHKK QSVQENLIHQ QDVDQGASDN YKQREKAVAA
     NKDYVLGHII QQETANPIDP ITLPDLQDKL GKLALHQTEP KQKPVKIAGI GEKKLGAVQE
     EKILVQKGQE AQADKVIQDN YNPVPDHGLH ENNNADAPAT INVEAKKEHI EKPKDGAVLE
     HDEGKQNRDL KLQNDMDLRR KKRDLALVQQ ENNGAQIISF HPVPNLKVND LRGALEARLN
     QMVDGGLQVV QSRKIKQLID EEKNR