S38AB_BOVIN
ID S38AB_BOVIN Reviewed; 463 AA.
AC Q5EA97;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Putative sodium-coupled neutral amino acid transporter 11;
DE AltName: Full=Solute carrier family 38 member 11;
GN Name=SLC38A11;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
CC -!- FUNCTION: Putative sodium-dependent amino acid/proton antiporter.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC {ECO:0000305}.
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DR EMBL; BT020672; AAX08689.1; -; mRNA.
DR RefSeq; NP_001026930.1; NM_001031760.1.
DR AlphaFoldDB; Q5EA97; -.
DR SMR; Q5EA97; -.
DR STRING; 9913.ENSBTAP00000010065; -.
DR PaxDb; Q5EA97; -.
DR GeneID; 523418; -.
DR KEGG; bta:523418; -.
DR CTD; 151258; -.
DR eggNOG; KOG1305; Eukaryota.
DR InParanoid; Q5EA97; -.
DR OrthoDB; 1109791at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR Pfam; PF01490; Aa_trans; 1.
PE 2: Evidence at transcript level;
KW Amino-acid transport; Glycoprotein; Ion transport; Membrane;
KW Reference proteome; Sodium; Sodium transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..463
FT /note="Putative sodium-coupled neutral amino acid
FT transporter 11"
FT /id="PRO_0000326058"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 397..417
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 437
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 442
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 458
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 463 AA; 50745 MW; A5BF810EF004BF1D CRC64;
MGYPGQRPVI PPQSHRDDRE TLVSEHKHKG KTCRQSAAVF NVVNSIIGSG IIGLPYSMKQ
AGFPLGILLL FWVSYVTDFS LILLIKGAAL SGTDTYQSLV NRTFGFPGYL LLSVLQFLYP
FIAMISYNII TGDTLSKVFQ RIPGVDPENL LIGRHLIIVL STVVFTLPLS LYRDIAKLGK
ISLISTVLTT LILGIVVARG VSLGPHIPKT EDAWIFAKPN AVQAVGVMSF AFICHHNCFL
VYGSLEEPTV AKWSHIIHVS TLISVFISIL FATCGYLTFT GYTQGDLFEN YCRNDDLVTF
GRFCYGVTVI LTYPIECFVT REVIANVFFG GNLSSVCHII VTVVIITVAT LVSLLIDCLG
IVLELNGVLC AAPLIFIIPS ACYLKLSEEP RTHSDKIMSC VMLPIGAVVM AVGFVMAVTS
PQDCSHGQEM FYCSPDNFSL TNISISHFQL TTQLSILNVS IFQ