ID   S38AB_DANRE             Reviewed;         448 AA.
AC   A8KBL5; Q568L8;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 11;
DE   AltName: Full=Solute carrier family 38 member 11;
GN   Name=slc38a11; ORFNames=zgc:110221;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative sodium-dependent amino acid/proton antiporter.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC       {ECO:0000305}.
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DR   EMBL; BC092805; AAH92805.1; -; mRNA.
DR   EMBL; BC154162; AAI54163.1; -; mRNA.
DR   RefSeq; NP_001017644.1; NM_001017644.1.
DR   AlphaFoldDB; A8KBL5; -.
DR   SMR; A8KBL5; -.
DR   STRING; 7955.ENSDARP00000058891; -.
DR   PaxDb; A8KBL5; -.
DR   Ensembl; ENSDART00000175587; ENSDARP00000144230; ENSDARG00000040257.
DR   GeneID; 550337; -.
DR   KEGG; dre:550337; -.
DR   CTD; 151258; -.
DR   ZFIN; ZDB-GENE-050417-122; slc38a11.
DR   eggNOG; KOG1305; Eukaryota.
DR   GeneTree; ENSGT00940000157782; -.
DR   HOGENOM; CLU_009020_4_2_1; -.
DR   InParanoid; A8KBL5; -.
DR   PhylomeDB; A8KBL5; -.
DR   TreeFam; TF328787; -.
DR   PRO; PR:A8KBL5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 9.
DR   Bgee; ENSDARG00000040257; Expressed in tail and 13 other tissues.
DR   ExpressionAtlas; A8KBL5; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR013057; AA_transpt_TM.
DR   Pfam; PF01490; Aa_trans; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid transport; Glycoprotein; Ion transport; Membrane;
KW   Reference proteome; Sodium; Sodium transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..448
FT                   /note="Putative sodium-coupled neutral amino acid
FT                   transporter 11"
FT                   /id="PRO_0000326062"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        324..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        346..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        425
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        440
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        444
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        111
FT                   /note="M -> V (in Ref. 1; AAH92805)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        332
FT                   /note="V -> G (in Ref. 1; AAH92805)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        342
FT                   /note="L -> P (in Ref. 1; AAH92805)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        426
FT                   /note="T -> I (in Ref. 1; AAI54163)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   448 AA;  48300 MW;  8A9A031D52A17224 CRC64;
     MESERSCLLS SHDAGKGGSS SVSSASFNFI NSIIGSGIIG LPYSMSQAGL PMGLLLLILV
     AFITDYSIIL LVRGGNLSGT HSYQSLVRST FGQIGYIIVS VLQFLYPFIA MISYNIIAGD
     TLTKVFMRIP GVGPGNILTE RHFVIAMSTV LFTLPLSLYR DIAKLGKVSL LSMILTFGIL
     MTVVVRAATL GPQIPASDDA WVFARWNAIQ AVAVMSFALI CHHNSFMIYG SLQEPTLSRW
     SLVTHISVGS SVLVSAVFAA AGYATFTVYT QGDIFENYCR SDNLATFGRF CYGVSIITTF
     PLECFVTREV ISNALFKGGE LSKSSHVIIT LVIISATTAI SLSYDCLGIV LELNGILSAV
     PLMFIFPSAC FLKLSNERWC RGENLIASMI LVAGVFVMII GLIMMALFPQ DCSHGAEMFY
     CSASNTSSTA SPSNILQFIN TTQNTSIV