S39A9_CHICK
ID S39A9_CHICK Reviewed; 305 AA.
AC Q5ZIU9;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Zinc transporter ZIP9;
DE AltName: Full=Solute carrier family 39 member 9;
DE AltName: Full=Zrt- and Irt-like protein 9;
DE Short=ZIP-9;
GN Name=SLC39A9; Synonyms=ZIP9; ORFNames=RCJMB04_23h6;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: May act as a zinc-influx transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; AJ720685; CAG32344.1; -; mRNA.
DR RefSeq; NP_001007934.1; NM_001007933.1.
DR AlphaFoldDB; Q5ZIU9; -.
DR SMR; Q5ZIU9; -.
DR STRING; 9031.ENSGALP00000041693; -.
DR PaxDb; Q5ZIU9; -.
DR Ensembl; ENSGALT00000015368; ENSGALP00000015352; ENSGALG00000009438.
DR GeneID; 423261; -.
DR KEGG; gga:423261; -.
DR CTD; 55334; -.
DR VEuPathDB; HostDB:geneid_423261; -.
DR eggNOG; KOG3907; Eukaryota.
DR GeneTree; ENSGT00390000010094; -.
DR HOGENOM; CLU_028824_1_0_1; -.
DR InParanoid; Q5ZIU9; -.
DR OrthoDB; 1388694at2759; -.
DR PhylomeDB; Q5ZIU9; -.
DR TreeFam; TF315051; -.
DR PRO; PR:Q5ZIU9; -.
DR Proteomes; UP000000539; Chromosome 5.
DR Bgee; ENSGALG00000009438; Expressed in testis and 13 other tissues.
DR ExpressionAtlas; Q5ZIU9; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR045891; ZIP9.
DR PANTHER; PTHR16133; PTHR16133; 1.
DR Pfam; PF02535; Zip; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport; Zinc; Zinc transport.
FT CHAIN 1..305
FT /note="Zinc transporter ZIP9"
FT /id="PRO_0000297602"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 29
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 239
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 305 AA; 32192 MW; F3A6E9566EBE1C9D CRC64;
MDDFRSICLL SLAMLVACYV AGIIPLAVNF SEERLKLVTV LGAGLLCGTA LAVIVPEGVH
ALYEDILEGK HHPANEMQHV MESEKVAEIA VVHEYGHDHS RLHAYIGVSL VLGFVFMLLV
DQIGSSHVHS TDDPEAARSG NSKITTTLGL VVHAAADGVA LGAAASTSQT SVQLIVFVAI
MLHKAPAAFG LVSFLMHAGL ERNRIRKHLL VFALAAPVMS MVTYLGLSKS SKEALSEVNA
TGVAMLFSAG TFLYVATVHV LPEVGGIAHS HRPESTGGKG LSRLEVAALV LGCLIPLVLS
IGHHH