ID   S39A9_DANRE             Reviewed;         309 AA.
AC   Q5BL29;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Zinc transporter ZIP9;
DE   AltName: Full=Solute carrier family 39 member 9;
DE   AltName: Full=Zrt- and Irt-like protein 9;
DE            Short=ZIP-9;
GN   Name=slc39a9; Synonyms=zip9; ORFNames=zgc:101628;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a zinc-influx transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC       {ECO:0000305}.
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DR   EMBL; BC090821; AAH90821.1; -; mRNA.
DR   RefSeq; NP_001013558.1; NM_001013540.1.
DR   AlphaFoldDB; Q5BL29; -.
DR   SMR; Q5BL29; -.
DR   STRING; 7955.ENSDARP00000094174; -.
DR   PaxDb; Q5BL29; -.
DR   Ensembl; ENSDART00000103397; ENSDARP00000094174; ENSDARG00000070447.
DR   GeneID; 541413; -.
DR   KEGG; dre:541413; -.
DR   CTD; 55334; -.
DR   ZFIN; ZDB-GENE-060314-3; slc39a9.
DR   eggNOG; KOG3907; Eukaryota.
DR   GeneTree; ENSGT00390000010094; -.
DR   HOGENOM; CLU_028824_1_0_1; -.
DR   InParanoid; Q5BL29; -.
DR   OMA; AAIMIHK; -.
DR   OrthoDB; 1388694at2759; -.
DR   PhylomeDB; Q5BL29; -.
DR   TreeFam; TF315051; -.
DR   PRO; PR:Q5BL29; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 17.
DR   Bgee; ENSDARG00000070447; Expressed in liver and 27 other tissues.
DR   ExpressionAtlas; Q5BL29; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; ISS:ZFIN.
DR   GO; GO:0006829; P:zinc ion transport; ISS:ZFIN.
DR   InterPro; IPR003689; ZIP.
DR   InterPro; IPR045891; ZIP9.
DR   PANTHER; PTHR16133; PTHR16133; 1.
DR   Pfam; PF02535; Zip; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Zinc; Zinc transport.
FT   CHAIN           1..309
FT                   /note="Zinc transporter ZIP9"
FT                   /id="PRO_0000297603"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        29
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        242
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   309 AA;  31908 MW;  E30ABC8850B30D6C CRC64;
     MDDFSSISLL SLSMLIGCYV AGTIPLAVNF SEEKLKLVTV LGAGLLCGTA LAVIIPEGVH
     ALYEEMLEGV HNHGHGQVEA EVSEQKVAEG VVRPSGEHGH GHEQLHAYIG ISLVLGFVFM
     LLVDQIGSAH MHSSDDPEAA RAASSKITTT LGLVVHAAAD GVALGAAAST SQTSVQLIVF
     VAIMLHKAPA AFGLVSFLMH AGLERNRIRK HLLVFALAAP VLAMVTYVGL SQSSKEALSD
     VNATGVAMLF SAGTFLYVAT VHVLPEVGGM GGHSHSPGGS AGKGLSKLEV GALVLGCLIP
     LVLSIGHQH