S39A9_MACFA
ID S39A9_MACFA Reviewed; 235 AA.
AC Q95JP5;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Zinc transporter ZIP9;
DE AltName: Full=Solute carrier family 39 member 9;
DE AltName: Full=Zrt- and Irt-like protein 9;
DE Short=ZIP-9;
GN Name=SLC39A9; Synonyms=ZIP9; ORFNames=QtsA-14752;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA Terao K., Sugano S., Hashimoto K.;
RT "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT the human genome sequence.";
RL BMC Genomics 3:36-36(2002).
CC -!- FUNCTION: May act as a zinc-influx transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; AB070136; BAB63081.1; -; mRNA.
DR AlphaFoldDB; Q95JP5; -.
DR SMR; Q95JP5; -.
DR STRING; 9541.XP_005561659.1; -.
DR eggNOG; KOG3907; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR045891; ZIP9.
DR PANTHER; PTHR16133; PTHR16133; 1.
DR Pfam; PF02535; Zip; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport; Zinc; Zinc transport.
FT CHAIN 1..235
FT /note="Zinc transporter ZIP9"
FT /id="PRO_0000297598"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 2
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 169
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 235 AA; 24993 MW; D5D728E1149BD3F0 CRC64;
MNMSTATTTH SCVPILVFPS YWASFSCCWW TRLVTPMCIL LTPTQCEDDE DENLYDDPLL
LNNPEAARSS NSKTTTTLGL VVHAAADGVA LGAAASTSQT SVQLIVFVAI MLHKAPAAFG
LVSFLMHAGL ERNRIRKHLL VFSLAAPVMS MVTYLGLSKS SKEALSEVNA TGMAMLFSAG
TFLYVATVHV LPEVGGIGHS HKPDATGGRG LSRLEVAALV LGCLIPLILS VGHQH