S39A9_RAT
ID S39A9_RAT Reviewed; 287 AA.
AC Q3KR82;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Zinc transporter ZIP9;
DE AltName: Full=Solute carrier family 39 member 9;
DE AltName: Full=Zrt- and Irt-like protein 9;
DE Short=ZIP-9;
GN Name=Slc39a9; Synonyms=Zip9;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May act as a zinc-influx transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; BC105849; AAI05850.1; -; mRNA.
DR RefSeq; NP_001030101.1; NM_001034929.1.
DR RefSeq; XP_017449635.1; XM_017594146.1.
DR AlphaFoldDB; Q3KR82; -.
DR SMR; Q3KR82; -.
DR STRING; 10116.ENSRNOP00000006798; -.
DR GlyGen; Q3KR82; 3 sites.
DR PaxDb; Q3KR82; -.
DR Ensembl; ENSRNOT00000006798; ENSRNOP00000006798; ENSRNOG00000005052.
DR GeneID; 314275; -.
DR KEGG; rno:314275; -.
DR UCSC; RGD:1311236; rat.
DR CTD; 55334; -.
DR RGD; 1311236; Slc39a9.
DR eggNOG; KOG3907; Eukaryota.
DR GeneTree; ENSGT00390000010094; -.
DR InParanoid; Q3KR82; -.
DR PhylomeDB; Q3KR82; -.
DR TreeFam; TF315051; -.
DR PRO; PR:Q3KR82; -.
DR Proteomes; UP000002494; Chromosome 6.
DR Bgee; ENSRNOG00000005052; Expressed in jejunum and 19 other tissues.
DR ExpressionAtlas; Q3KR82; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR003689; ZIP.
DR InterPro; IPR045891; ZIP9.
DR PANTHER; PTHR16133; PTHR16133; 1.
DR Pfam; PF02535; Zip; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport; Zinc; Zinc transport.
FT CHAIN 1..287
FT /note="Zinc transporter ZIP9"
FT /id="PRO_0000297601"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 268..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 29
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 242
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 271
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 287 AA; 30177 MW; 7FF4A9914167428D CRC64;
MDDFLSISLL SLAMLVGCYV AGIIPLAVNF SEERLKLVTV LGAGLLCGTA LAVIVPEGVH
ALYEEVLEGK HHQASEAKQN VIASDKAAEI SVVHEHEHSH DHTQLHAYIG VSLVLGFVFM
LLVDQIGSSH VHSTDDPESA RPSSSKITTT LGLVVHAAAD GVALGAAAST SQTSVQLIVF
VAIMLHKAPA AFGLVSFLMH AGLERNRIRK HLLVFALAAP AMSMLTYLGL SKSSKEALSE
VNATGVAMLF SAGTFLYVAT VHVLPEDTST NQSGSSLSPR PLPSGKN
