ID   S39A9_XENTR             Reviewed;         303 AA.
AC   Q640S1;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Zinc transporter ZIP9;
DE   AltName: Full=Solute carrier family 39 member 9;
DE   AltName: Full=Zrt- and Irt-like protein 9;
DE            Short=ZIP-9;
GN   Name=slc39a9; Synonyms=zip9;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a zinc-influx transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC       {ECO:0000305}.
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DR   EMBL; BC082518; AAH82518.1; -; mRNA.
DR   RefSeq; NP_001008193.1; NM_001008192.1.
DR   RefSeq; XP_012823729.1; XM_012968275.2.
DR   RefSeq; XP_012823730.1; XM_012968276.2.
DR   AlphaFoldDB; Q640S1; -.
DR   SMR; Q640S1; -.
DR   STRING; 8364.ENSXETP00000038810; -.
DR   PaxDb; Q640S1; -.
DR   DNASU; 493555; -.
DR   Ensembl; ENSXETT00000038810; ENSXETP00000038810; ENSXETG00000017909.
DR   GeneID; 493555; -.
DR   KEGG; xtr:493555; -.
DR   CTD; 55334; -.
DR   Xenbase; XB-GENE-943772; slc39a9.
DR   eggNOG; KOG3907; Eukaryota.
DR   HOGENOM; CLU_028824_1_0_1; -.
DR   InParanoid; Q640S1; -.
DR   OMA; HYFGHSA; -.
DR   OrthoDB; 1388694at2759; -.
DR   PhylomeDB; Q640S1; -.
DR   TreeFam; TF315051; -.
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000017909; Expressed in 4-cell stage embryo and 14 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003689; ZIP.
DR   InterPro; IPR045891; ZIP9.
DR   PANTHER; PTHR16133; PTHR16133; 1.
DR   Pfam; PF02535; Zip; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Zinc; Zinc transport.
FT   CHAIN           1..303
FT                   /note="Zinc transporter ZIP9"
FT                   /id="PRO_0000297606"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        29
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        237
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   303 AA;  31645 MW;  83D407F3044F9200 CRC64;
     MDDFSSISLL SLAMLVGCYV SGIIPLAVNF SEEKLKLVTV LGAGLLCGTA LAVIVPEGVH
     ALYEEVLEAK HHDMGDIHKA KDAETGAEIS AAHEHDHSNL HAYIGVSLVL GFVFMLLVDQ
     IGSSHMHSAD DPEAARAASS KITTTLGLVV HAAADGVALG AAASTSQTSV QLIVFVAIML
     HKAPAAFGLV SFLMHAGLER NRIRKHLLVF ALAAPVLSML TYLGLSKSSK EALSEVNATG
     VAMLFSAGTF LYVATVHVLP EVGGMGHSHK PEVGATKGLS RLEVCALVLG CLIPLVLSIG
     HQH