S39AB_BOVIN
ID S39AB_BOVIN Reviewed; 341 AA.
AC Q2YDD4;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Zinc transporter ZIP11;
DE AltName: Full=Solute carrier family 39 member 11;
DE AltName: Full=Zrt- and Irt-like protein 11;
DE Short=ZIP-11;
GN Name=SLC39A11; Synonyms=ZIP11;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Functions as a cellular zinc transporter.
CC {ECO:0000250|UniProtKB:Q8BWY7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8BWY7};
CC Multi-pass membrane protein {ECO:0000305}. Nucleus
CC {ECO:0000250|UniProtKB:Q8BWY7}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q8BWY7}. Golgi apparatus
CC {ECO:0000250|UniProtKB:Q8BWY7}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000305}.
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DR EMBL; BC110274; AAI10275.1; -; mRNA.
DR RefSeq; NP_001069858.1; NM_001076390.1.
DR RefSeq; XP_005221326.1; XM_005221269.3.
DR AlphaFoldDB; Q2YDD4; -.
DR SMR; Q2YDD4; -.
DR STRING; 9913.ENSBTAP00000025078; -.
DR PaxDb; Q2YDD4; -.
DR PRIDE; Q2YDD4; -.
DR Ensembl; ENSBTAT00000025078; ENSBTAP00000025078; ENSBTAG00000018837.
DR GeneID; 615681; -.
DR KEGG; bta:615681; -.
DR CTD; 201266; -.
DR VEuPathDB; HostDB:ENSBTAG00000018837; -.
DR VGNC; VGNC:34859; SLC39A11.
DR eggNOG; KOG2474; Eukaryota.
DR GeneTree; ENSGT00390000006167; -.
DR HOGENOM; CLU_015114_1_1_1; -.
DR InParanoid; Q2YDD4; -.
DR OMA; MIFVVIE; -.
DR OrthoDB; 892454at2759; -.
DR TreeFam; TF105905; -.
DR Proteomes; UP000009136; Chromosome 19.
DR Bgee; ENSBTAG00000018837; Expressed in saliva-secreting gland and 104 other tissues.
DR ExpressionAtlas; Q2YDD4; baseline.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; ISS:UniProtKB.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR Pfam; PF02535; Zip; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Cytoplasm; Golgi apparatus; Ion transport; Membrane;
KW Nucleus; Reference proteome; Transmembrane; Transmembrane helix; Transport;
KW Zinc; Zinc transport.
FT CHAIN 1..341
FT /note="Zinc transporter ZIP11"
FT /id="PRO_0000308409"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 262..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 289..306
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 341 AA; 35198 MW; 5CEE18EBBF0C601C CRC64;
MLHGHSPVSQ ALLGTFFTWG LTAAGAALVF VFSSGQRRIL DGSLGFAAGV MLAASYWSLL
APAVEMAMSS GGFGSLAFLP VAIGFTLGAA FVYVADLLMP HWGAAEDPQT ALALNLDPLL
TKKSDAEGAR MLFPESELSI RIGRAGLLSD KSENGEAYQR KRAVATDLAE GPAAPGPPRG
SAAQPGGSSW RRIALLILAI TIHNIPEGLA VGVGFGAVGK TASATFESAR NLALGIGIQN
FPEGLAVSLP LRGAGFSTWR AFWYGQLSGM VEPLAGVFGA FAVVLAEPIL PYALAFAAGA
MVYVIMDDII PEAQISGNGK LASWASILGF VVMMSLDVGL G
