S40A1_ORYSJ
ID S40A1_ORYSJ Reviewed; 484 AA.
AC Q5Z922; A0A0P0WXZ5;
DT 21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Solute carrier family 40 member 1;
GN OrderedLocusNames=Os06g0560000, LOC_Os06g36450; ORFNames=P0528E12.13;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: May be involved in iron transport and iron homeostasis.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000305}.
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DR EMBL; AP003713; BAD53732.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF19781.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS98244.1; -; Genomic_DNA.
DR EMBL; AK063490; BAG88730.1; -; mRNA.
DR EMBL; AK101863; BAG95262.1; -; mRNA.
DR RefSeq; XP_015641654.1; XM_015786168.1.
DR AlphaFoldDB; Q5Z922; -.
DR SMR; Q5Z922; -.
DR STRING; 4530.OS06T0560000-01; -.
DR PaxDb; Q5Z922; -.
DR PRIDE; Q5Z922; -.
DR EnsemblPlants; Os06t0560000-01; Os06t0560000-01; Os06g0560000.
DR EnsemblPlants; Os06t0560000-02; Os06t0560000-02; Os06g0560000.
DR GeneID; 4341302; -.
DR Gramene; Os06t0560000-01; Os06t0560000-01; Os06g0560000.
DR Gramene; Os06t0560000-02; Os06t0560000-02; Os06g0560000.
DR KEGG; osa:4341302; -.
DR eggNOG; KOG2601; Eukaryota.
DR HOGENOM; CLU_020370_1_0_1; -.
DR InParanoid; Q5Z922; -.
DR OMA; NVHELEH; -.
DR OrthoDB; 334057at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q5Z922; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006826; P:iron ion transport; IBA:GO_Central.
DR CDD; cd17480; MFS_SLC40A1_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11660; PTHR11660; 1.
DR Pfam; PF06963; FPN1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Ion transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..484
FT /note="Solute carrier family 40 member 1"
FT /id="PRO_0000415901"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 377..397
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 442..462
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 484 AA; 52015 MW; 1F6B0B37CD5CD02A CRC64;
MASDGHLAAP LLDGGGGVDD AALLRRLYVG HFLARWGARM WEFSVGLYMI RIWPGSLLLT
AVYGVVEASA VAALGPIVGA VVDRLAYLQV LRLWLLLQGA SFVAAGVSVT ALLVYGARLA
AAGFPAFVAL VVVTNVSGAL AALSTLAGTI LIEREWVVVI AGGQPAAVLT GINSVIRRID
LSCKLLAPVL SGFFISFVSM EASAAALAAW NLAAVWVQYW LFVSVYAGFP ALSETSQISR
RRADDDEAAA AAQPQKVERL WMTMLPCWES WAVYARQEVV LPGVALAFLY FTVLSFGTLM
TATLDWEGIP AYVISLARGV SAAVGIAATW VYPAAHARVS TLRAGLWSIW AQWCCLLVCV
ASVWAGGAAP LASAWMLMGG VAASRLGLWM FDLAVMQLMQ DGVPESDRCV VGGVQNSLQS
MFDLLTYVMG IIVSDPRDFG ELIVLSFFLV TCAAAMYTMH VYRVRKHLFH LDRILPKMNW
IKAS
