S40A2_ORYSJ
ID S40A2_ORYSJ Reviewed; 591 AA.
AC Q2QNK7; A0A0P0YBB2; Q2QNK5; Q2QNK6;
DT 21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Solute carrier family 40 member 2, chloroplastic;
DE Flags: Precursor;
GN OrderedLocusNames=Os12g0562100, LOC_Os12g37530;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: May be involved in iron transport and iron homeostasis.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Plastid, chloroplast envelope {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q2QNK7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q2QNK7-2; Sequence=VSP_042415;
CC -!- SIMILARITY: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABA98948.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DP000011; ABA98946.1; -; Genomic_DNA.
DR EMBL; DP000011; ABA98947.1; -; Genomic_DNA.
DR EMBL; DP000011; ABA98948.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008218; BAF30045.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT17649.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT17650.1; -; Genomic_DNA.
DR EMBL; AK064831; BAG89229.1; -; mRNA.
DR EMBL; AK065844; BAG89702.1; -; mRNA.
DR RefSeq; XP_015620078.1; XM_015764592.1. [Q2QNK7-1]
DR AlphaFoldDB; Q2QNK7; -.
DR SMR; Q2QNK7; -.
DR STRING; 4530.OS12T0562100-01; -.
DR PaxDb; Q2QNK7; -.
DR PRIDE; Q2QNK7; -.
DR EnsemblPlants; Os12t0562100-01; Os12t0562100-01; Os12g0562100. [Q2QNK7-1]
DR EnsemblPlants; Os12t0562100-02; Os12t0562100-02; Os12g0562100. [Q2QNK7-2]
DR GeneID; 4352522; -.
DR Gramene; Os12t0562100-01; Os12t0562100-01; Os12g0562100. [Q2QNK7-1]
DR Gramene; Os12t0562100-02; Os12t0562100-02; Os12g0562100. [Q2QNK7-2]
DR KEGG; osa:4352522; -.
DR eggNOG; KOG2601; Eukaryota.
DR InParanoid; Q2QNK7; -.
DR OMA; CGLMICS; -.
DR OrthoDB; 334057at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR Genevisible; Q2QNK7; OS.
DR GO; GO:0009941; C:chloroplast envelope; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006826; P:iron ion transport; IBA:GO_Central.
DR CDD; cd17480; MFS_SLC40A1_like; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR009716; Ferroportin-1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11660; PTHR11660; 1.
DR Pfam; PF06963; FPN1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Chloroplast; Ion transport; Membrane; Plastid;
KW Reference proteome; Transit peptide; Transmembrane; Transmembrane helix;
KW Transport.
FT TRANSIT 1..66
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 67..591
FT /note="Solute carrier family 40 member 2, chloroplastic"
FT /id="PRO_0000415902"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 419..439
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 482..502
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 518..540
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 547..569
FT /note="Helical"
FT /evidence="ECO:0000255"
FT VAR_SEQ 591
FT /note="I -> M (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_042415"
SQ SEQUENCE 591 AA; 62776 MW; C515787CF671B665 CRC64;
MGMVTATAAA ALLASPPQGH LGRRCHLVVP GLRLRPPASS SPPHAAPPLR LSNFVPRCYI
TNVEVDVSHT SEQEALDDHP PLLPACAIPV VHLRDVPDAS PFPLHESASH STDFEELPVL
SEGELHTIAA TPAHPAGLYA LYASYLFGNL VEQLWNFAWP AALAILHPSL LPVAIVGFFT
KLSVFIGAPI VGKLMDHFPR IPMYTGLNAV QVATQLISAA MVIYAMKNVT HASTSAVVLK
PWFIALVAAG AIERLAGLAL GVAMERDWVV LLAGTNRPVA LAQANAVLNR LDLVCETVGA
SVFGLLLSKY HPVTCLKIAC GLMICSFPVL VVLGQLINRF SCHALDSSRT PSEESICANL
LDVRKIVQNG LSAIRNGWNE YKQQTVLPAS VATVFLNFNV ALAPGAIMTA LLMHRGISPS
IVGAFSGLCS IMGLVATFIS SSLVERVGIL KAGAAGLIVQ ASLLSVALVV YWTGSISQRT
PLLIFLAAIA LSRLGHMSYD VVGTQILQTG VPASKANLIG GMEVSISSLA ELVMLGMAII
ANDVSHFGFL AILSVSSVAG AAWMFCQWLG NPTDEQRELF MFDPHFQVEP I
