ID   S40B_CHITE              Reviewed;         253 AA.
AC   Q05019;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Salivary gland SP38-40.B protein;
DE   Flags: Precursor;
GN   Name=SP38-40.B;
OS   Chironomus tentans (Midge) (Camptochironomus tentans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7153;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8510150; DOI=10.1006/jmbi.1993.1285;
RA   Galli J., Wieslander L.;
RT   "Two secretory protein genes in Chironomus tentans have arisen by gene
RT   duplication and exhibit different developmental expression patterns.";
RL   J. Mol. Biol. 231:324-334(1993).
CC   -!- FUNCTION: Used by the larvae to construct a supramolecular structure,
CC       the larval tube.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Salivary gland.
CC   -!- DEVELOPMENTAL STAGE: Expression of the SP38-40.a and B genes are
CC       different: the A gene is expressed throughout the larval fourth instar
CC       but considerably less in the prepupal stage, while the B gene shows the
CC       opposite expression pattern.
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DR   EMBL; X70063; CAA49668.1; -; Genomic_DNA.
DR   PIR; S33820; S33820.
DR   AlphaFoldDB; Q05019; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Repeat; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..253
FT                   /note="Salivary gland SP38-40.B protein"
FT                   /id="PRO_0000022264"
FT   REPEAT          29..34
FT                   /note="1-1"
FT   REPEAT          35..40
FT                   /note="1-2"
FT   REPEAT          41..47
FT                   /note="1-3; approximate"
FT   REPEAT          153..156
FT                   /note="2-1"
FT   REPEAT          158..161
FT                   /note="2-2"
FT   REPEAT          162..166
FT                   /note="2-3; approximate"
FT   REPEAT          222..225
FT                   /note="3-1"
FT   REPEAT          226..229
FT                   /note="3-2"
FT   REPEAT          230..233
FT                   /note="3-3"
FT   REPEAT          234..237
FT                   /note="3-4"
FT   REPEAT          238..241
FT                   /note="3-5"
FT   REPEAT          242..245
FT                   /note="3-6"
FT   REPEAT          246..249
FT                   /note="3-7; approximate"
FT   REGION          23..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          29..47
FT                   /note="3 X 6 AA approximate tandem repeats of K-P-K-D-A-P"
FT   REGION          140..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          153..166
FT                   /note="3 X 4 AA approximate tandem repeats of K-P-P-K"
FT   REGION          203..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          222..249
FT                   /note="7 X 4 AA approximate tandem repeats of P-K-P-[GAV]"
FT   COMPBIAS        28..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..241
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   253 AA;  28372 MW;  ED825395994970D1 CRC64;
     MRIKFLVVLA VICLLAHYAS ASGMGGDKKP KDAPKPKDAP KPKEVKPVKA DSSEYEIEVI
     KHQKEKTEKK EKEKKAHVEI KKKIKNKEKK FVPCSEILKD EKLECEKNAT PGYKALFEFK
     ESESFCEWEC DYEAIPGAKK DEKKEKKVVK VIKPPKEKPP KKPRKECSGE KVIKFQNCLV
     KIRGLIAFGD KTKNFDKKFA KLVQGKQKKG AKKAKGGKKA EPKPGPKPAP KPGPKPAPKP
     VPKPADKPKD AKK