S45A3_MACFA
ID S45A3_MACFA Reviewed; 553 AA.
AC Q95KI5; Q95KC5;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 59.
DE RecName: Full=Solute carrier family 45 member 3;
DE AltName: Full=Prostate cancer-associated protein 6;
DE AltName: Full=Prostein;
GN Name=SLC45A3; Synonyms=PCANAP6, PRST; ORFNames=QmoA-10594, QtrA-11310;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Medulla oblongata, and Temporal cortex;
RA Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirai M., Terao K.,
RA Suzuki Y., Sugano S., Hashimoto K.;
RT "Isolation of full-length cDNA clones from macaque brain cDNA libraries.";
RL Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) cation
CC symporter transporter (TC 2.A.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB60745.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AB060851; BAB46871.1; -; mRNA.
DR EMBL; AB062977; BAB60745.1; ALT_INIT; mRNA.
DR AlphaFoldDB; Q95KI5; -.
DR STRING; 9541.XP_005540658.1; -.
DR PRIDE; Q95KI5; -.
DR eggNOG; KOG0637; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..553
FT /note="Solute carrier family 45 member 3"
FT /id="PRO_0000122520"
FT TRANSMEM 19..39
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 52..72
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 161..181
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 198..218
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 275..295
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TRANSMEM 382..402
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TRANSMEM 522..542
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT CONFLICT 165
FT /note="A -> T (in Ref. 1; BAB60745)"
FT /evidence="ECO:0000305"
FT CONFLICT 342
FT /note="M -> V (in Ref. 1; BAB60745)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 553 AA; 59393 MW; 0718F3A91FB3BF1E CRC64;
MVQRLWVSRL LRHRKAQLLL INLLTFGLEV CLAAGITYVP PLLLEVGVEE KFMTMVLGIG
PVLGLVSVPL LGSASDHWRG RYGRRRPFIW ALSLGILLSL FLIPRAGWLA GLLCPDPRPL
ELALLILGVG LLDFCGQVCF TPLEALLSDL FRDPDHCRQA YSVYAFMISL GGCLGYLLPA
IDWDTSALAP YLGTQEECLF GLLTLIFLTC VAATLLVAEE AALGPAEPAE GLSAPSLPSH
CCPCWARLAF RNLGALLPRL HQLCCRMPRT LRRLFVAELC SWMALMTFTL FYTDFVGEGL
YQGVPRAELG TEARRHYDEG VRMGSLGLFL QCAISLVFSL VMDRLVQRFG TRAVYLASVA
AFPVAAGATC LSHSVAVVTA SAALTGFTFS ALQILPYTLA SLYHRERQVF LPKYRGDAGG
TSSEDSLMTS FLPGPKPGAP FPNGHVGAGG SGLLPPPPAL CGASACDVSV RVVVGEPTEA
RVVPGRGICL DLAILDSAFL LSQVAPSLFM GSIVQLSQSV TAYMVSAAGL GLVAIYFATQ
VVFDKSDLAK YSV
