S49A3_DANRE
ID S49A3_DANRE Reviewed; 474 AA.
AC Q503P5;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Solute carrier family 49 member A3;
DE AltName: Full=Major facilitator superfamily domain-containing protein 7;
GN Name=slc49a3; Synonyms=mfsd7; ORFNames=zgc:110376;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000305}.
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DR EMBL; BC095234; AAH95234.1; -; mRNA.
DR RefSeq; NP_001018423.1; NM_001020587.1.
DR AlphaFoldDB; Q503P5; -.
DR PaxDb; Q503P5; -.
DR GeneID; 103908782; -.
DR KEGG; dre:103908782; -.
DR CTD; 84179; -.
DR ZFIN; ZDB-GENE-050522-300; slc49a3.
DR InParanoid; Q503P5; -.
DR OrthoDB; 702737at2759; -.
DR PhylomeDB; Q503P5; -.
DR PRO; PR:Q503P5; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..474
FT /note="Solute carrier family 49 member A3"
FT /id="PRO_0000273410"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 50190 MW; B7DCCD56B88B98BE CRC64;
MEGESAETEP LIQSSSAADR PDPAAEAAAR FTVYRRRWFI LSVLCLLNCS NAMAWLTFAP
VAGQSAQLLC VSLPLVNWLS LVFVLAAVVC SFSSMWVLDT LGLRCSLIGS SWLNACGCVL
RVCGVLSVTP QWAVFAVVMC GQTLCALAQP LVIFAPTKLA ALWFPDHQRA TANMLASMAN
TVGLLLANLL SPLIVSYSGD LFLLLLIYSI PAAVACLLAT LGIHQAVPPT PASASSSSSA
SEPFLQGIRQ LLRNRAYWIL LLCFGSGIGI FTCFSTLLEQ ILCVKGYSNG FAGVCGAVSI
VCGVAGAFLL SLYVDRSKKF MEVMKICMCL TSVSCSAFAV VSQLPAQSVL LVLVCCCFGL
FGYSVYPVGM ELSVETTHPL GEATSAGLIF TSGQIQAALY LLLLQALATP THSPTSVCAA
DTSLNWTVPV LVMAGVCAIS SCVFVVFFHT EYRRLRAEAD SATEPEPTGD AADA
