S7A6O_BOVIN
ID S7A6O_BOVIN Reviewed; 307 AA.
AC Q1JQE2;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Probable RNA polymerase II nuclear localization protein SLC7A6OS;
DE AltName: Full=Solute carrier family 7 member 6 opposite strand transcript homolog;
GN Name=SLC7A6OS;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Uterus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Directs RNA polymerase II nuclear import. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IWR1/SLC7A6OS family. {ECO:0000305}.
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DR EMBL; BC116007; AAI16008.1; -; mRNA.
DR RefSeq; NP_001069035.1; NM_001075567.1.
DR AlphaFoldDB; Q1JQE2; -.
DR STRING; 9913.ENSBTAP00000012698; -.
DR PaxDb; Q1JQE2; -.
DR PRIDE; Q1JQE2; -.
DR Ensembl; ENSBTAT00000012698; ENSBTAP00000012698; ENSBTAG00000009636.
DR GeneID; 512543; -.
DR KEGG; bta:512543; -.
DR CTD; 84138; -.
DR VEuPathDB; HostDB:ENSBTAG00000009636; -.
DR eggNOG; KOG4852; Eukaryota.
DR GeneTree; ENSGT00390000015672; -.
DR HOGENOM; CLU_059743_0_0_1; -.
DR InParanoid; Q1JQE2; -.
DR OMA; YPDEDEF; -.
DR OrthoDB; 1160014at2759; -.
DR TreeFam; TF324404; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000009636; Expressed in thymus and 105 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032502; P:developmental process; IBA:GO_Central.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR040218; SLC7A6OS.
DR InterPro; IPR013883; TF_Iwr1_dom.
DR PANTHER; PTHR31196; PTHR31196; 1.
DR Pfam; PF08574; Iwr1; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Phosphoprotein; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..307
FT /note="Probable RNA polymerase II nuclear localization
FT protein SLC7A6OS"
FT /id="PRO_0000289168"
FT REGION 233..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..307
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 300
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96CW6"
FT MOD_RES 306
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96CW6"
SQ SEQUENCE 307 AA; 34762 MW; 17F494D2E4617195 CRC64;
MEAGRTAVLR VKRKLGTEPA EALVLACKRL RSSAVELETP KTSPEGLERA AENNVFQLVA
TVRSQEEPVQ PLLRAALRPS QGSQQRIRHH LRASAREIRQ EGRYRVVFSR RSSGIPSDSL
ESEDASGTAK AADDANFQLL DLVHEEDAEV AAAAISCKKS DPDVILCNCV ELIREGLNVS
QCGPSSGHQK EQKDDFVYDI YCLERATPGW IENILSVQPY SHEWELVNDD QQPEDIYDDE
DDENSENNWR NEYPEEENSD EDEDSRGSDN YSSSEERDNS RQPMWSKYPL DVQKEFDYDS
PHDLDSD