S7A6O_XENLA
ID S7A6O_XENLA Reviewed; 313 AA.
AC A2BDB7;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 38.
DE RecName: Full=Probable RNA polymerase II nuclear localization protein SLC7A6OS;
DE AltName: Full=Solute carrier family 7 member 6 opposite strand transcript homolog;
GN Name=slc7a6os;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Directs RNA polymerase II nuclear import. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the IWR1/SLC7A6OS family. {ECO:0000305}.
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DR EMBL; BC130167; AAI30168.1; -; mRNA.
DR RefSeq; NP_001091280.1; NM_001097811.1.
DR AlphaFoldDB; A2BDB7; -.
DR BioGRID; 674370; 1.
DR IntAct; A2BDB7; 1.
DR DNASU; 100037092; -.
DR GeneID; 100037092; -.
DR KEGG; xla:100037092; -.
DR CTD; 100037092; -.
DR Xenbase; XB-GENE-5805743; slc7a6os.L.
DR OrthoDB; 1160014at2759; -.
DR Proteomes; UP000186698; Chromosome 4L.
DR Bgee; 100037092; Expressed in egg cell and 19 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR040218; SLC7A6OS.
DR InterPro; IPR013883; TF_Iwr1_dom.
DR PANTHER; PTHR31196; PTHR31196; 1.
DR Pfam; PF08574; Iwr1; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Protein transport; Reference proteome; Transport.
FT CHAIN 1..313
FT /note="Probable RNA polymerase II nuclear localization
FT protein SLC7A6OS"
FT /id="PRO_0000289172"
FT REGION 76..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 127..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..262
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 36426 MW; 29B1C0DF45373E6C CRC64;
MEAAVLRVKR KRGADPADAL ILSCKRIRTE DETKESSAVT TQVFRLAATV KSENEPLHKY
VREAISRNQS CLTLRPSSES KQRIQEELRA SKEAERQVSR YRIISSHRPN SEEDNVGASH
LIGCSSQDVP SETQDEAEAT EATKSHISSP FQLFDMVQEE PEQKYLEKDS EPETILCNSI
KMIREHLTVS EAGQESEHRE YVDEYVYDIY YSEASQHGWI QDILYVQPYT EEQELVSEEP
EPEEIYEDED DENEENNWRN DYPDEEDSDR EERYIGYYED GDEEEKSAGH AWKMYHRSSL
REIGDDDENA DLY