ID   ABCGN_DICDI             Reviewed;         701 AA.
AC   Q55EH8;
DT   09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=ABC transporter G family member 23;
DE   AltName: Full=ABC transporter ABCG.23;
GN   Name=abcG23; ORFNames=DDB_G0269026;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000004; EAL73102.2; -; Genomic_DNA.
DR   RefSeq; XP_647042.2; XM_641950.2.
DR   AlphaFoldDB; Q55EH8; -.
DR   SMR; Q55EH8; -.
DR   STRING; 44689.DDB0304677; -.
DR   PaxDb; Q55EH8; -.
DR   EnsemblProtists; EAL73102; EAL73102; DDB_G0269026.
DR   GeneID; 8616737; -.
DR   KEGG; ddi:DDB_G0269026; -.
DR   dictyBase; DDB_G0269026; abcG23.
DR   eggNOG; KOG0059; Eukaryota.
DR   HOGENOM; CLU_014367_1_0_1; -.
DR   InParanoid; Q55EH8; -.
DR   OMA; QQFCPVH; -.
DR   PhylomeDB; Q55EH8; -.
DR   PRO; PR:Q55EH8; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..701
FT                   /note="ABC transporter G family member 23"
FT                   /id="PRO_0000391406"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        493..513
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        541..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        574..596
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        608..628
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        665..685
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          7..237
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          459..686
FT                   /note="ABC transmembrane type-2"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   701 AA;  78738 MW;  7EAB8C7D51D4AF05 CRC64;
     MGDNIVINLN NVSRSYGNVK VIEKLNFTIN KGTINSLIGS SGSGKTTILK TILGKLKQDD
     GIVQVFGKEP CGKGSEIPGS SVGYAPQDVC LYNEITIEET LSFFASIHRM PKDEYIKKRD
     SLVEILELPS LSKIISELSG GQQRRVSLAT ALIHSPKLLI LDEPTVGVCP LVSSKIWEHL
     IFLTKNFGVT IIITTHYLQE CRSCDNIFLL RNGRILESGP PNYLLSKYEC SLLEDVYYKL
     CRGDEEISLQ LIDSKNNEKI NRDINTSIPL EFISNGANIN NDDILISNTN KPIIKKDAKI
     YKERLSDFKN KLQIWFSHSI TISIRKLTQM YRLKFPLVFE IISPSLLITL FFLAIGNVPH
     DLKFGIKNID SGSLSGDFIN ALSDGNNIFN FIQINDTSNA IQMIESSDLW GLIDIPVNFT
     NGMINKLFNP LEKSFENSEM EIYMDLSNFQ MNLMVDVQFQ KAFNKIANDS GIKLLPTNFH
     AVYGDQNANF NWFLAPAMIC IITYVHCMNF LSITFVREKN DGTRDRILLY GVSPVSNVLG
     HILAHIPILL VQFSIQLLIA VFAFGVPIKG NIVLIYLFFI LINTVGMCQG ILISLISKAE
     VDAVQLCLAI FICSLCMAGI IWPTEAIITF GWISNLVPTK WSGLALRGIM IKDLPFSHQH
     IWKSLIIIIS YIIGTFSLIV ISTPIGDRNF NFKKLFKRIK K