ID   SAA2_PIG                Reviewed;         129 AA.
AC   P0DSO0;
DT   17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT   17-JUN-2020, sequence version 1.
DT   25-MAY-2022, entry version 10.
DE   RecName: Full=Serum amyloid A-2 protein {ECO:0000250|UniProtKB:P0DJI9};
DE   Contains:
DE     RecName: Full=Amyloid protein AA1 {ECO:0000250|UniProtKB:P02739};
DE     AltName: Full=Protein AA1 {ECO:0000250|UniProtKB:P02739};
DE              Short=AA1 {ECO:0000250|UniProtKB:P02739};
DE   Contains:
DE     RecName: Full=Amyloid protein AA2 {ECO:0000250|UniProtKB:P02739};
DE     AltName: Full=Protein AA2 {ECO:0000250|UniProtKB:P02739};
DE              Short=AA2 {ECO:0000250|UniProtKB:P02739};
DE   Flags: Precursor;
GN   Name=SAA2 {ECO:0000250|UniProtKB:P0DJI9};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc;
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Major acute phase reactant. {ECO:0000250|UniProtKB:P05366}.
CC   -!- SUBUNIT: Apolipoprotein of the HDL complex.
CC       {ECO:0000250|UniProtKB:P0DJI8}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0DJI8}.
CC   -!- SIMILARITY: Belongs to the SAA family. {ECO:0000305}.
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DR   EMBL; JH114990; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003122985.1; XM_003122937.3.
DR   RefSeq; XP_005661152.1; XM_005661095.2.
DR   AlphaFoldDB; P0DSO0; -.
DR   SMR; P0DSO0; -.
DR   Ensembl; ENSSSCT00030084562; ENSSSCP00030038920; ENSSSCG00030060455.
DR   Ensembl; ENSSSCT00040073111; ENSSSCP00040031274; ENSSSCG00040054034.
DR   GeneID; 100525680; -.
DR   KEGG; ssc:100525680; -.
DR   CTD; 6289; -.
DR   Proteomes; UP000008227; Unplaced.
DR   Proteomes; UP000314985; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000096; Serum_amyloid_A.
DR   Pfam; PF00277; SAA; 1.
DR   PIRSF; PIRSF002472; Serum_amyloid_A; 1.
DR   PRINTS; PR00306; SERUMAMYLOID.
DR   SMART; SM00197; SAA; 1.
DR   PROSITE; PS00992; SAA; 1.
PE   3: Inferred from homology;
KW   Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000250|UniProtKB:P02739"
FT   CHAIN           19..129
FT                   /note="Serum amyloid A-2 protein"
FT                   /evidence="ECO:0000250|UniProtKB:P02739"
FT                   /id="PRO_0000450366"
FT   CHAIN           19..82
FT                   /note="Amyloid protein AA1"
FT                   /evidence="ECO:0000250|UniProtKB:P02739"
FT                   /id="PRO_0000450367"
FT   CHAIN           19..71
FT                   /note="Amyloid protein AA2"
FT                   /evidence="ECO:0000250|UniProtKB:P02739"
FT                   /id="PRO_0000450368"
FT   REGION          90..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         19
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250|UniProtKB:P02739"
SQ   SEQUENCE   129 AA;  14418 MW;  13080B78832DABB3 CRC64;
     MKLFTGLIFC SLVLGVHSQW LSFLGEAYEG AKDMLRAYSD MREANFKNSD KYFHARGNYD
     AAQRGPGGAW AAKVISDARE NVQRVTDWLK HGDSGHGVED SRADQAANEW GRSGKDPNHF
     RPPGLPDKY