ID   SAA4_BOVIN              Reviewed;         129 AA.
AC   Q32L76;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Serum amyloid A-4 protein {ECO:0000250|UniProtKB:P35542};
DE   Flags: Precursor;
GN   Name=SAA4 {ECO:0000250|UniProtKB:P35542};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Major acute phase reactant. {ECO:0000250|UniProtKB:P05366}.
CC   -!- SUBUNIT: Apolipoprotein of the HDL complex.
CC       {ECO:0000250|UniProtKB:P0DJI8}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0DJI8}.
CC   -!- SIMILARITY: Belongs to the SAA family. {ECO:0000305}.
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DR   EMBL; BC109725; AAI09726.1; -; mRNA.
DR   RefSeq; NP_001035595.1; NM_001040505.2.
DR   AlphaFoldDB; Q32L76; -.
DR   SMR; Q32L76; -.
DR   STRING; 9913.ENSBTAP00000003858; -.
DR   PaxDb; Q32L76; -.
DR   PRIDE; Q32L76; -.
DR   Ensembl; ENSBTAT00000003858; ENSBTAP00000003858; ENSBTAG00000002963.
DR   GeneID; 505308; -.
DR   KEGG; bta:505308; -.
DR   CTD; 6291; -.
DR   VEuPathDB; HostDB:ENSBTAG00000002963; -.
DR   eggNOG; ENOG502S4PB; Eukaryota.
DR   GeneTree; ENSGT00390000004737; -.
DR   HOGENOM; CLU_129936_0_0_1; -.
DR   InParanoid; Q32L76; -.
DR   OMA; YPNSERY; -.
DR   OrthoDB; 1417043at2759; -.
DR   TreeFam; TF332544; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000002963; Expressed in semen and 30 other tissues.
DR   GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-KW.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   InterPro; IPR000096; Serum_amyloid_A.
DR   Pfam; PF00277; SAA; 1.
DR   PIRSF; PIRSF002472; Serum_amyloid_A; 1.
DR   PRINTS; PR00306; SERUMAMYLOID.
DR   SMART; SM00197; SAA; 1.
DR   PROSITE; PS00992; SAA; 1.
PE   2: Evidence at transcript level;
KW   Acute phase; HDL; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..129
FT                   /note="Serum amyloid A-4 protein"
FT                   /id="PRO_0000282886"
FT   REGION          107..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   129 AA;  14688 MW;  B8E4DC9BED854A55 CRC64;
     MKLLIGILFC TLIMGVTGDS WYSFFKEAVQ GASDLWRAYW DMRDANVQNS GRYFRARGNY
     EAAQRGPGGV WAAKIISNVG EYLQGFLYQI YLGDSYGLED QVSNRRAEEW GRSGQDPDHF
     RPAGLPKKY