SAA4_PIG
ID SAA4_PIG Reviewed; 128 AA.
AC P0DSN9;
DT 17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT 17-JUN-2020, sequence version 1.
DT 25-MAY-2022, entry version 7.
DE RecName: Full=Serum amyloid A-4 protein {ECO:0000250|UniProtKB:P35542};
DE Flags: Precursor;
GN Name=SAA4 {ECO:0000250|UniProtKB:P35542};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Porcine genome sequencing project;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Major acute phase reactant. {ECO:0000250|UniProtKB:P05366}.
CC -!- SUBUNIT: Apolipoprotein of the HDL complex.
CC {ECO:0000250|UniProtKB:P0DJI8}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0DJI8}.
CC -!- SIMILARITY: Belongs to the SAA family. {ECO:0000305}.
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DR EMBL; CM000813; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003122987.1; XM_003122939.2.
DR AlphaFoldDB; P0DSN9; -.
DR SMR; P0DSN9; -.
DR Ensembl; ENSSSCT00025015360; ENSSSCP00025006041; ENSSSCG00025011644.
DR Ensembl; ENSSSCT00030084690; ENSSSCP00030038978; ENSSSCG00030060625.
DR Ensembl; ENSSSCT00040072871; ENSSSCP00040031154; ENSSSCG00040053874.
DR Ensembl; ENSSSCT00055023793; ENSSSCP00055018818; ENSSSCG00055012171.
DR Ensembl; ENSSSCT00055023847; ENSSSCP00055018865; ENSSSCG00055012171.
DR Ensembl; ENSSSCT00060033008; ENSSSCP00060014155; ENSSSCG00060024336.
DR Ensembl; ENSSSCT00070014700; ENSSSCP00070012143; ENSSSCG00070007616.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Chromosome 2.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR000096; Serum_amyloid_A.
DR Pfam; PF00277; SAA; 1.
DR PIRSF; PIRSF002472; Serum_amyloid_A; 1.
DR PRINTS; PR00306; SERUMAMYLOID.
DR SMART; SM00197; SAA; 1.
DR PROSITE; PS00992; SAA; 1.
PE 3: Inferred from homology;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..128
FT /note="Serum amyloid A-4 protein"
FT /evidence="ECO:0000255"
FT /id="PRO_0000450369"
FT REGION 93..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 128 AA; 14591 MW; 650017467823BC6E CRC64;
MKLFIGLIFC SLVMGVSSDG WFSFFKEAVQ GASDLWRAYW DMKEANYQNS GRYFRARGNY
EAAQRGPGGI WAAKIISNVG EYFQGLLQYL GSSSEREEDQ VSNRRAEEWG RSGQDPDHFR
PAGLPKKY