ID   SAA_NOTEU               Reviewed;         127 AA.
AC   P53613;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Serum amyloid A protein;
DE            Short=SAA;
DE   Flags: Precursor;
GN   Name=SAA1;
OS   Notamacropus eugenii (Tammar wallaby) (Macropus eugenii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Macropodidae; Notamacropus.
OX   NCBI_TaxID=9315;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Liver;
RX   PubMed=8602460; DOI=10.1046/j.1365-3083.1996.d01-34.x;
RA   Uhlar C.M., Black I.L., Shields D.C., Brack C.M., Schreiber G.,
RA   Whitehead A.S.;
RT   "Wallaby serum amyloid A protein: cDNA cloning, sequence and evolutionary
RT   analysis.";
RL   Scand. J. Immunol. 43:271-276(1996).
CC   -!- FUNCTION: Major acute phase reactant. Apolipoprotein of the HDL
CC       complex.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the liver; secreted in plasma.
CC   -!- SIMILARITY: Belongs to the SAA family. {ECO:0000305}.
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DR   EMBL; U39363; AAB02187.1; -; mRNA.
DR   AlphaFoldDB; P53613; -.
DR   SMR; P53613; -.
DR   HOGENOM; CLU_129936_0_0_1; -.
DR   TreeFam; TF332544; -.
DR   GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-KW.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   InterPro; IPR000096; Serum_amyloid_A.
DR   Pfam; PF00277; SAA; 1.
DR   PIRSF; PIRSF002472; Serum_amyloid_A; 1.
DR   PRINTS; PR00306; SERUMAMYLOID.
DR   SMART; SM00197; SAA; 1.
DR   PROSITE; PS00992; SAA; 1.
PE   2: Evidence at transcript level;
KW   Acute phase; HDL; Pyrrolidone carboxylic acid; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..127
FT                   /note="Serum amyloid A protein"
FT                   /id="PRO_0000031584"
FT   REGION          89..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..127
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         19
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250|UniProtKB:P42819"
SQ   SEQUENCE   127 AA;  14322 MW;  D2405776418F48FB CRC64;
     MKLLTSLFLL SLVLCVNSQG WLRDSLDFLN QARLGAGDMW RAYRDMREAN FKNSDKYFHA
     RGNYDAAKRG PGGVWAAEVL SDAREFLQGG SSGRGVEDSM ADQEANRWGR SGKDPNRYRP
     KGLDPKY