SAC31_SCHPO
ID SAC31_SCHPO Reviewed; 1024 AA.
AC O74889;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=SAC3 family protein 1;
GN ORFNames=SPCC576.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAA21184.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-841, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC envelope {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the SAC3 family. {ECO:0000255}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329672; CAA21184.1; -; Genomic_DNA.
DR PIR; T41415; T41415.
DR RefSeq; NP_588432.1; NM_001023423.2.
DR AlphaFoldDB; O74889; -.
DR SMR; O74889; -.
DR BioGRID; 276122; 2.
DR STRING; 4896.SPCC576.05.1; -.
DR iPTMnet; O74889; -.
DR MaxQB; O74889; -.
DR PaxDb; O74889; -.
DR PRIDE; O74889; -.
DR EnsemblFungi; SPCC576.05.1; SPCC576.05.1:pep; SPCC576.05.
DR GeneID; 2539561; -.
DR KEGG; spo:SPCC576.05; -.
DR PomBase; SPCC576.05; -.
DR VEuPathDB; FungiDB:SPCC576.05; -.
DR eggNOG; KOG1860; Eukaryota.
DR HOGENOM; CLU_298457_0_0_1; -.
DR InParanoid; O74889; -.
DR OMA; VACHERI; -.
DR PhylomeDB; O74889; -.
DR PRO; PR:O74889; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005635; C:nuclear envelope; HDA:PomBase.
DR GO; GO:0005643; C:nuclear pore; ISO:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0070390; C:transcription export complex 2; IBA:GO_Central.
DR GO; GO:0006406; P:mRNA export from nucleus; ISO:PomBase.
DR GO; GO:0006611; P:protein export from nucleus; ISO:PomBase.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; ISO:PomBase.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR017173; Sac3.
DR InterPro; IPR045107; SAC3/GANP/THP3.
DR InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR PANTHER; PTHR12436; PTHR12436; 1.
DR Pfam; PF03399; SAC3_GANP; 1.
DR PIRSF; PIRSF037320; mRNA_export_factor_Sac3; 1.
DR PROSITE; PS50250; PCI; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..1024
FT /note="SAC3 family protein 1"
FT /id="PRO_0000316863"
FT DOMAIN 243..433
FT /note="PCI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 945..1022
FT /evidence="ECO:0000255"
FT COMPBIAS 20..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 841
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 1024 AA; 117664 MW; D036FCB208FB9A8B CRC64;
MEKRNETGNN RLKRSNNRGK SKKDWKDASV ETTPRETSVD EDNTSVFEDV EAQDSRQKRF
SSTLEGNRFE ELRSLREKER EVAIQNGLID DPTKPRQLDE AVTFVGTCPD MCPEYEREQR
EYQNNLERWE INPETGRVDK NLAVKAFHRP AAGNEQALPS DVRPPPVLKK SLDYLVDKIV
CGPDPLENTH FFVRDRTRSI RQDFTLQNCR DLDAVACHER IARYHILCIH QLCEKKQFSA
QQEVEQLRKG ILQSLCEFYD DLRKVKIRCP NEPEFRSYAI ITHLRDPDVV RQSQILPIEI
FDDQRVQLAL RLSALAQKNN ERVGHILPRN TEACPNLYTR FFKLVQSPAV TYLMACLLES
HFMSIRKGAL KAMRKAFMSA HANFPCGDLK RILHFDTVEQ AASFSRYYGL EVSDDNGELS
INLNKTAFFN DSKPDFRQLF SQTLVESKLQ NRSFADIING SRYNIDRVSP NTAFSTNIPL
SLPFANKEPQ PIAGFKKNTP ETSVVSKNLS TFNGKFNVNA PVFTPRSFPT KPFSATDISS
VQPTNLPNGS TNGTETFIPP VQNSITSNKE AVKPIKNKPK PISFESLSAV GNLIISDSLS
RIVRQILQNL YTEWVHEKTN LVFATMFRTI FREVLLDGIA SEVYLKSLKK HAISQISVRA
HHSWVKKQEK MMLEMREKNR QEKYFSVLNS VVKAESSNIT RLPIKRTFYG DTRNLDKASE
KLRAEHDRTR RLWKPVLMDS LFSNLQKFPV YEDWHLLIFN ASTSSMMKTW LCAKFSLKET
NKTSFWHSSY NLFNRQYHVD MPDNVSDLPQ TRLCYGACVY NVGLLDEEKR KDLANSDLNS
SPKLIQGNDS RSAHESSANK LFSFVHDISR LTITKLPLLL IFWSDSNLDM QGITQKYRFL
ELITSTWSAI SSIHVLTITN DRDMDLEHSL KVLLDNVTVE KSPFAQLEEL EVVRKKREAE
IEASSKTVKR LASNNKFLTD SNVEGLLEAP TSLENSLVED DKWASLRQKI KAARDLLKKV
ETFY
