SAC32_SCHPO
ID SAC32_SCHPO Reviewed; 458 AA.
AC Q9USI4;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=SAC3 family protein 2;
GN ORFNames=SPCC70.06;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAB62160.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus,
CC nucleolus {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the SAC3 family. {ECO:0000255}.
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DR EMBL; CU329672; CAB62160.1; -; Genomic_DNA.
DR RefSeq; NP_588540.1; NM_001023528.2.
DR AlphaFoldDB; Q9USI4; -.
DR SMR; Q9USI4; -.
DR BioGRID; 276127; 34.
DR STRING; 4896.SPCC70.06.1; -.
DR iPTMnet; Q9USI4; -.
DR MaxQB; Q9USI4; -.
DR PaxDb; Q9USI4; -.
DR EnsemblFungi; SPCC70.06.1; SPCC70.06.1:pep; SPCC70.06.
DR GeneID; 2539567; -.
DR KEGG; spo:SPCC70.06; -.
DR PomBase; SPCC70.06; -.
DR VEuPathDB; FungiDB:SPCC70.06; -.
DR eggNOG; KOG1860; Eukaryota.
DR HOGENOM; CLU_047746_2_1_1; -.
DR InParanoid; Q9USI4; -.
DR OMA; AQRNNHT; -.
DR PhylomeDB; Q9USI4; -.
DR PRO; PR:Q9USI4; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0070390; C:transcription export complex 2; IBA:GO_Central.
DR GO; GO:0006406; P:mRNA export from nucleus; IBA:GO_Central.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR045107; SAC3/GANP/THP3.
DR InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR PANTHER; PTHR12436; PTHR12436; 1.
DR Pfam; PF03399; SAC3_GANP; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..458
FT /note="SAC3 family protein 2"
FT /id="PRO_0000316864"
FT DOMAIN 211..411
FT /note="PCI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 458 AA; 52334 MW; F07C956113DFD056 CRC64;
MSTKVKQKQK QKHRPKPSLD RSDSTKRAAR AARFSTTLDA NFQALKKKRK DEQESFQAKQ
STNWEKSSVL VGTCRQMCPE FELEERKLQH AIHPYELDPV SKQAHPSLAV KAYHRPAAGK
GPILPSDVRP PSILKNTIDY LFKVILDRYS LREAHAFVRD RTRAVRQDFS VQSSFSQDSV
YCHELIARFH IISLHELAHT PNFSRQQEIE QLSKSMEILY TLGQLYDYMH LRKEHCTHEA
EFRAYMVLLS LGDPSVGLDT LSWPDFVFKK PIVKTSLKLY SLAQRNNHTI TTSNSISLSL
VSSFNTEATS NLYTRFFKIA SSFRVSYLMG CLLDLFVPSI RTGALKAMKK CYLSAHSNIP
FKDLMKILAA TSEDELVQCC KMHGLKIEYI GEQPSAVVLN RKTVITEPLL SSEISCRFAD
EKKPGTNVSD LICLDTDGSS LHRKKPKLFK KRSIVRQR