ID   SAC51_ARATH             Reviewed;         348 AA.
AC   Q9FMF4;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Transcription factor SAC51;
DE   AltName: Full=Basic helix-loop-helix protein 142;
DE            Short=AtbHLH142;
DE            Short=bHLH 142;
DE   AltName: Full=Protein SUPPRESSOR OF ACAULIS 51;
DE   AltName: Full=Transcription factor EN 128;
DE   AltName: Full=bHLH transcription factor bHLH142;
GN   Name=SAC51; Synonyms=BHLH142, EN128; OrderedLocusNames=At5g64340;
GN   ORFNames=MSJ1.18;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA   Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT   features of the regions of 1,191,918 bp covered by seventeen physically
RT   assigned P1 clones.";
RL   DNA Res. 4:401-414(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12897250; DOI=10.1105/tpc.013839;
RA   Toledo-Ortiz G., Huq E., Quail P.H.;
RT   "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL   Plant Cell 15:1749-1770(2003).
RN   [5]
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=16936072; DOI=10.1242/dev.02535;
RA   Imai A., Hanzawa Y., Komura M., Yamamoto K.T., Komeda Y., Takahashi T.;
RT   "The dwarf phenotype of the Arabidopsis acl5 mutant is suppressed by a
RT   mutation in an upstream ORF of a bHLH gene.";
RL   Development 133:3575-3585(2006).
CC   -!- FUNCTION: Transcription factor. Involved in stem elongation, probably
CC       by regulating a subset of genes involved in this process.
CC       {ECO:0000269|PubMed:16936072}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
CC   -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, stems, leaves, and
CC       flowers. {ECO:0000269|PubMed:16936072}.
CC   -!- SIMILARITY: Belongs to the bHLH protein family. {ECO:0000305}.
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DR   EMBL; AB008268; BAB09865.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED97872.1; -; Genomic_DNA.
DR   EMBL; AY062561; AAL32639.1; -; mRNA.
DR   EMBL; AY093333; AAM13332.1; -; mRNA.
DR   RefSeq; NP_201239.1; NM_125830.2.
DR   AlphaFoldDB; Q9FMF4; -.
DR   SMR; Q9FMF4; -.
DR   BioGRID; 21797; 15.
DR   IntAct; Q9FMF4; 15.
DR   STRING; 3702.AT5G64340.1; -.
DR   PaxDb; Q9FMF4; -.
DR   PRIDE; Q9FMF4; -.
DR   EnsemblPlants; AT5G64340.1; AT5G64340.1; AT5G64340.
DR   GeneID; 836555; -.
DR   Gramene; AT5G64340.1; AT5G64340.1; AT5G64340.
DR   KEGG; ath:AT5G64340; -.
DR   Araport; AT5G64340; -.
DR   TAIR; locus:2173433; AT5G64340.
DR   eggNOG; ENOG502S1PH; Eukaryota.
DR   HOGENOM; CLU_053960_0_0_1; -.
DR   InParanoid; Q9FMF4; -.
DR   OMA; EDIDSPC; -.
DR   OrthoDB; 1201232at2759; -.
DR   PhylomeDB; Q9FMF4; -.
DR   PRO; PR:Q9FMF4; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FMF4; baseline and differential.
DR   Genevisible; Q9FMF4; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   GO; GO:0009826; P:unidimensional cell growth; IMP:TAIR.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR037546; SAC51-like.
DR   PANTHER; PTHR36066; PTHR36066; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..348
FT                   /note="Transcription factor SAC51"
FT                   /id="PRO_0000358854"
FT   DOMAIN          260..309
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT   REGION          179..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   348 AA;  38702 MW;  62FCFC5735CB8EAE CRC64;
     MPLDKRQRDL PLGLSPQACF KDIVGRSVLP RIPLPELGKL YAAKLQARCL QPPPFQSLLC
     SHDKESYGKR FSRSDMRSWC AAATTTTTPL GALESSQKRL LIFDQSGDQT RLLQCPFPLR
     FPSHAAAEPV KLSELQGIEK AFKEDGEEFH KSDGTESEMH EDTEEINALL YSDDDYDDDC
     ESDDEVMSTG HSPYPNEGVC NKRELEEIDG PCKRQKLLDK VNNISDLSSL VGTESSTQLN
     GSSFLKDKKL PESKTISTKE DTGSGLSNEQ SKKDKIRTAL KILESVVPGA KGNEALLLLD
     EAIDYLKLLK RDLISTEVKN QSSTTHKSPI LLLKETTWGT RNLQTDKA