SACDR_BOVIN
ID SACDR_BOVIN Reviewed; 204 AA.
AC Q2T9X5;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 55.
DE RecName: Full=Sperm acrosome developmental regulator;
GN Name=SPACDR;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play an important role in acrosome formation and nucleus
CC shaping during spermiogenesis. {ECO:0000250|UniProtKB:Q8IZ16}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome
CC {ECO:0000250|UniProtKB:Q8IZ16}. Note=Detected in acrosome of round
CC spermatids and spermatozoa. {ECO:0000250|UniProtKB:Q8IZ16}.
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DR EMBL; BC111222; AAI11223.1; -; mRNA.
DR RefSeq; NP_001069954.1; NM_001076486.2.
DR AlphaFoldDB; Q2T9X5; -.
DR SMR; Q2T9X5; -.
DR STRING; 9913.ENSBTAP00000022295; -.
DR PaxDb; Q2T9X5; -.
DR PRIDE; Q2T9X5; -.
DR GeneID; 617958; -.
DR KEGG; bta:617958; -.
DR CTD; 402573; -.
DR eggNOG; ENOG502TM6R; Eukaryota.
DR OrthoDB; 1476149at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0001669; C:acrosomal vesicle; ISS:UniProtKB.
DR GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
DR InterPro; IPR031534; DUF4703.
DR PANTHER; PTHR39221; PTHR39221; 1.
DR Pfam; PF15775; DUF4703; 1.
PE 2: Evidence at transcript level;
KW Cytoplasmic vesicle; Differentiation; Phosphoprotein; Reference proteome;
KW Spermatogenesis.
FT CHAIN 1..204
FT /note="Sperm acrosome developmental regulator"
FT /id="PRO_0000325781"
FT REGION 172..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 65
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AY52"
SQ SEQUENCE 204 AA; 23438 MW; 46E94A879B6317CD CRC64;
MAVVIKFFRW IWQKISRWVF FWKHKAKSVI MDHTDSKKNE LKAEKAFKVS ETFKLVEPPK
EAKVSKMDVS PKVVDPCLLA KTTMDGAAVE AGRRRRSLLK LPQAAVKSVS MLMASALQSG
WQMCSWKSSV SSTSVASQMK TRSPLESREA AMLREVYLVL WAIRKQLRQV ARRQERRRRH
HLRAHMGPQP DPAQGLKQDA RSPL