ID   SACDR_RAT               Reviewed;         200 AA.
AC   Q6AY52;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Sperm acrosome developmental regulator;
GN   Name=Spacdr;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-63, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- FUNCTION: May play an important role in acrosome formation and nucleus
CC       shaping during spermiogenesis. {ECO:0000250|UniProtKB:Q8IZ16}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome
CC       {ECO:0000250|UniProtKB:Q8IZ16}. Note=Detected in acrosome of round
CC       spermatids and spermatozoa. {ECO:0000250|UniProtKB:Q8IZ16}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC079190; AAH79190.1; -; mRNA.
DR   RefSeq; NP_001258165.1; NM_001271236.1.
DR   RefSeq; XP_017453988.1; XM_017598499.1.
DR   AlphaFoldDB; Q6AY52; -.
DR   SMR; Q6AY52; -.
DR   STRING; 10116.ENSRNOP00000056351; -.
DR   iPTMnet; Q6AY52; -.
DR   PhosphoSitePlus; Q6AY52; -.
DR   PaxDb; Q6AY52; -.
DR   GeneID; 100362783; -.
DR   KEGG; rno:100362783; -.
DR   UCSC; RGD:1584380; rat.
DR   CTD; 100362783; -.
DR   RGD; 2324075; LOC100362783.
DR   VEuPathDB; HostDB:ENSRNOG00000050805; -.
DR   eggNOG; ENOG502TM6R; Eukaryota.
DR   HOGENOM; CLU_1360014_0_0_1; -.
DR   OMA; WRKITCW; -.
DR   OrthoDB; 1476149at2759; -.
DR   PRO; PR:Q6AY52; -.
DR   Proteomes; UP000002494; Chromosome 12.
DR   Bgee; ENSRNOG00000024616; Expressed in heart and 19 other tissues.
DR   ExpressionAtlas; Q6AY52; baseline and differential.
DR   Genevisible; Q6AY52; RN.
DR   GO; GO:0001669; C:acrosomal vesicle; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
DR   InterPro; IPR031534; DUF4703.
DR   PANTHER; PTHR39221; PTHR39221; 1.
DR   Pfam; PF15775; DUF4703; 1.
PE   1: Evidence at protein level;
KW   Cytoplasmic vesicle; Differentiation; Phosphoprotein; Reference proteome;
KW   Spermatogenesis.
FT   CHAIN           1..200
FT                   /note="Sperm acrosome developmental regulator"
FT                   /id="PRO_0000325783"
FT   REGION          167..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..200
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         63
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   200 AA;  23486 MW;  68252C67D9680AA7 CRC64;
     MRFLRWIRQI WRKVPNWVLF WKHLAKPGLS DQREKHLLKG PEKTSKDFDT VKLANAQKED
     MVSDLDVCPG VLRSVKERSP LHDRESRSSR DSRSLMTVVN SVSTFMFSVL QSGWRLCRWK
     SSMSTGKVSS HTRTGSALGT PEAEMLREVY LVLWVIRKQL RELARRQERR RRRRMRSHAS
     HTSRHSESVQ GLKHDARSPL