ID   SAM12_MOUSE             Reviewed;         161 AA.
AC   Q0VE29;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Sterile alpha motif domain-containing protein 12;
DE            Short=SAM domain-containing protein 12;
GN   Name=Samd12;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC119385; AAI19386.1; -; mRNA.
DR   EMBL; BC119383; AAI19384.1; -; mRNA.
DR   CCDS; CCDS37072.1; -.
DR   RefSeq; NP_796199.1; NM_177225.4.
DR   AlphaFoldDB; Q0VE29; -.
DR   SMR; Q0VE29; -.
DR   STRING; 10090.ENSMUSP00000077741; -.
DR   iPTMnet; Q0VE29; -.
DR   PhosphoSitePlus; Q0VE29; -.
DR   PaxDb; Q0VE29; -.
DR   PRIDE; Q0VE29; -.
DR   ProteomicsDB; 256830; -.
DR   Antibodypedia; 13629; 78 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000078673; ENSMUSP00000077741; ENSMUSG00000058656.
DR   GeneID; 320679; -.
DR   KEGG; mmu:320679; -.
DR   UCSC; uc007vri.1; mouse.
DR   CTD; 401474; -.
DR   MGI; MGI:2444518; Samd12.
DR   VEuPathDB; HostDB:ENSMUSG00000058656; -.
DR   eggNOG; ENOG502RXXU; Eukaryota.
DR   GeneTree; ENSGT00390000008161; -.
DR   HOGENOM; CLU_105476_0_0_1; -.
DR   InParanoid; Q0VE29; -.
DR   OMA; PSGWMEG; -.
DR   OrthoDB; 1479834at2759; -.
DR   PhylomeDB; Q0VE29; -.
DR   TreeFam; TF325918; -.
DR   BioGRID-ORCS; 320679; 2 hits in 71 CRISPR screens.
DR   ChiTaRS; Samd12; mouse.
DR   PRO; PR:Q0VE29; -.
DR   Proteomes; UP000000589; Chromosome 15.
DR   RNAct; Q0VE29; protein.
DR   Bgee; ENSMUSG00000058656; Expressed in lumbar dorsal root ganglion and 135 other tissues.
DR   ExpressionAtlas; Q0VE29; baseline and differential.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IBA:GO_Central.
DR   CDD; cd09510; SAM_aveugle-like; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR039144; Aveugle-like_SAM_dom.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   Pfam; PF07647; SAM_2; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..161
FT                   /note="Sterile alpha motif domain-containing protein 12"
FT                   /id="PRO_0000279503"
FT   DOMAIN          77..143
FT                   /note="SAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00184"
FT   REGION          44..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   161 AA;  18245 MW;  BC3759A104C315D8 CRC64;
     MAVEALHCGL NPRGIDHSAH ADGIKLQIEG EGVESQSIKN RTFQKVPDQK GTPKRLQGEA
     ETAKSATVKL SKPVALWTQQ DVCKWLKKHC PNQYQLYSES FKQHDITGRA LLRLTDKKLE
     RMGIAQENQR QHILQQVLQL KVREEVRNLQ LLTQASVECS P