ID   SAM15_MOUSE             Reviewed;         620 AA.
AC   F6XZJ7;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Sterile alpha motif domain-containing protein 15;
DE            Short=SAM domain-containing protein 15;
GN   Name=Samd15; Synonyms=Gm263;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
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DR   EMBL; AC132609; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS70409.1; -.
DR   RefSeq; NP_001277217.1; NM_001290288.1.
DR   AlphaFoldDB; F6XZJ7; -.
DR   SMR; F6XZJ7; -.
DR   STRING; 10090.ENSMUSP00000138551; -.
DR   PhosphoSitePlus; F6XZJ7; -.
DR   PaxDb; F6XZJ7; -.
DR   PRIDE; F6XZJ7; -.
DR   ProteomicsDB; 256696; -.
DR   Antibodypedia; 26042; 54 antibodies from 14 providers.
DR   Ensembl; ENSMUST00000182869; ENSMUSP00000138551; ENSMUSG00000090812.
DR   GeneID; 238333; -.
DR   KEGG; mmu:238333; -.
DR   UCSC; uc056yrs.1; mouse.
DR   CTD; 161394; -.
DR   MGI; MGI:2685109; Samd15.
DR   VEuPathDB; HostDB:ENSMUSG00000090812; -.
DR   eggNOG; ENOG502S3Z4; Eukaryota.
DR   GeneTree; ENSGT00630000089942; -.
DR   HOGENOM; CLU_028120_0_0_1; -.
DR   InParanoid; F6XZJ7; -.
DR   OMA; MGEFFKD; -.
DR   OrthoDB; 532179at2759; -.
DR   PhylomeDB; F6XZJ7; -.
DR   BioGRID-ORCS; 238333; 0 hits in 50 CRISPR screens.
DR   ChiTaRS; Samd15; mouse.
DR   PRO; PR:F6XZJ7; -.
DR   Proteomes; UP000000589; Chromosome 12.
DR   RNAct; F6XZJ7; protein.
DR   Bgee; ENSMUSG00000090812; Expressed in testis and 57 other tissues.
DR   ExpressionAtlas; F6XZJ7; baseline and differential.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR042554; SAMD15.
DR   PANTHER; PTHR46829; PTHR46829; 2.
DR   Pfam; PF00536; SAM_1; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..620
FT                   /note="Sterile alpha motif domain-containing protein 15"
FT                   /id="PRO_0000416123"
FT   DOMAIN          480..543
FT                   /note="SAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00184"
FT   REGION          1..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          594..620
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..180
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..254
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..287
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..386
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   620 AA;  70457 MW;  6E7E0B795A433308 CRC64;
     MSEVSGDYNS DSDESLSLQP KRTKSGKLHN ANADTLFEVS SKLSPNTDRD PGNVGNVPLE
     PTRTRKGDLV PVGKNHEVPD LQRQDVSVGV FKGPPTRTGT QLPTKIDPEQ KTPDIRSEKL
     RKSVEEEALP PSKMTKSEKK QKESIKEKST EPYEVTKPKF PDRKLRKSTE EADLKPHFKS
     TEQSGTEQPE QTKFPDKKLR QSTKKKVSGP LEDFEEESRR PIDEASLELS QKRPLKASKK
     AQKSSFDEKF PEMLEQITVE LLDDQEETQE ESIKEKVPEP LGDRKPSAQK HKLRKSSERS
     KLKDTLIEPS KDKDPGLQTQ TEFPKEKLIK TTEKTGDKPQ QITDPDIQEK SQPEPTEKNL
     ELPNKPKPEE ERDLPKEDKP ESSKPNYPAG KDKLALPAKI KTEFIVGSPR ESVESFSTLY
     ETQEFLKDLQ TDMNELFPIV DASESQTELR DSTVLPQEVE LLGRKETKPS LTPEFEHLTW
     SPERVAEWIS DLGFPQYKEC FTENFINGQK LIHVNCSNLP QMGITDFEDM KAISYHTRVL
     LGIEEPLFSR SISLPYRDNK GLFFEQKGHS GVKSDSLTLA KFVEAAGLQE YNPEIKAEEK
     KEDALPENSL EENEELYEAT