ID   SAM50_XENTR             Reviewed;         468 AA.
AC   Q6P806;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Sorting and assembly machinery component 50 homolog;
GN   Name=samm50;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the maintenance of the structure of
CC       mitochondrial cristae. {ECO:0000250|UniProtKB:Q9Y512}.
CC   -!- SUBUNIT: Associates with the mitochondrial contact site and cristae
CC       organizing system (MICOS) complex (also known as MINOS or MitOS
CC       complex). {ECO:0000250|UniProtKB:Q9Y512}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000250|UniProtKB:Q9Y512}; Multi-pass membrane protein
CC       {ECO:0000250}.
CC   -!- DOMAIN: Its C-terminal part seems to contain many membrane-spanning
CC       sided beta-sheets, that have the potential to adopt a transmembrane
CC       beta-barrel type structure. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SAM50/omp85 family. {ECO:0000305}.
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DR   EMBL; BC061425; AAH61425.1; -; mRNA.
DR   RefSeq; NP_989138.1; NM_203807.1.
DR   AlphaFoldDB; Q6P806; -.
DR   SMR; Q6P806; -.
DR   DNASU; 394743; -.
DR   GeneID; 394743; -.
DR   KEGG; xtr:394743; -.
DR   CTD; 25813; -.
DR   Xenbase; XB-GENE-6456163; samm50.
DR   InParanoid; Q6P806; -.
DR   OrthoDB; 844748at2759; -.
DR   Reactome; R-XTR-9013404; RAC2 GTPase cycle.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000004871; Expressed in skeletal muscle tissue and 13 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0001401; C:SAM complex; IBA:GO_Central.
DR   GO; GO:0042407; P:cristae formation; ISS:UniProtKB.
DR   GO; GO:0033108; P:mitochondrial respiratory chain complex assembly; IBA:GO_Central.
DR   GO; GO:0045040; P:protein insertion into mitochondrial outer membrane; IBA:GO_Central.
DR   InterPro; IPR000184; Bac_surfAg_D15.
DR   InterPro; IPR039910; D15-like.
DR   InterPro; IPR034746; POTRA.
DR   PANTHER; PTHR12815; PTHR12815; 1.
DR   Pfam; PF01103; Omp85; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome;
KW   Transmembrane; Transmembrane beta strand.
FT   CHAIN           1..468
FT                   /note="Sorting and assembly machinery component 50 homolog"
FT                   /id="PRO_0000383685"
FT   DOMAIN          44..124
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   468 AA;  52150 MW;  9B8CD65040C9D40B CRC64;
     MGTVHARSLD PLPMNGPDFG SHDDADLVEV EPQKKQEILE NKDVVVQRVH FEGLGRTKDD
     LIAHEIGQVF KAKNLIEVMR KSHEAREKLL RLGVFRNVEV LIDTCEGEDA LPNGLDVTFE
     VTELRRLTGS YNTMVGNNEG SMVLGLKLPN LFGRAEKMTF QFSYGTKETS YGLSFFKPQV
     GNFERNFSVN LYKVTGQFPW SSLRETDRGV SAEINFPIWK TSHTLKWEGV WRELGCLART
     ASFAIREESG HTLKSSLSHT MVIDSRNTSI LPKRGALLKI NQELAGYTGG DVSFLKEDFE
     LQLNKQLAWD SVLSTSLWGG MLVPIGDKPS SIADRFYLGG PTSVRGFSMY SIGPQSEGDY
     LGGEAYWAGG MHLYTPLPFR PGRGGFGDLF RTHFFLNAGN LCNLNYGEGP RAHLRRLAEC
     IRWSYGAGIV LRLGNIARLE LNYCIPMGVQ SGDRICDGVQ FGAGIRFL