ID   SAM5B_XENLA             Reviewed;         468 AA.
AC   Q6PA35;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Sorting and assembly machinery component 50 homolog B;
GN   Name=samm50-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the maintenance of the structure of
CC       mitochondrial cristae. {ECO:0000250|UniProtKB:Q9Y512}.
CC   -!- SUBUNIT: Associates with the mitochondrial contact site and cristae
CC       organizing system (MICOS) complex (also known as MINOS or MitOS
CC       complex). {ECO:0000250|UniProtKB:Q9Y512}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000250|UniProtKB:Q9Y512}; Multi-pass membrane protein
CC       {ECO:0000250}.
CC   -!- DOMAIN: Its C-terminal part seems to contain many membrane-spanning
CC       sided beta-sheets, that have the potential to adopt a transmembrane
CC       beta-barrel type structure. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SAM50/omp85 family. {ECO:0000305}.
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DR   EMBL; BC060470; AAH60470.1; -; mRNA.
DR   RefSeq; NP_001083329.1; NM_001089860.1.
DR   AlphaFoldDB; Q6PA35; -.
DR   SMR; Q6PA35; -.
DR   DNASU; 398869; -.
DR   GeneID; 398869; -.
DR   KEGG; xla:398869; -.
DR   CTD; 398869; -.
DR   Xenbase; XB-GENE-6255146; samm50.S.
DR   OrthoDB; 844748at2759; -.
DR   Proteomes; UP000186698; Chromosome 3S.
DR   Bgee; 398869; Expressed in muscle tissue and 20 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042407; P:cristae formation; ISS:UniProtKB.
DR   InterPro; IPR000184; Bac_surfAg_D15.
DR   InterPro; IPR010827; BamA/TamA_POTRA.
DR   InterPro; IPR039910; D15-like.
DR   InterPro; IPR034746; POTRA.
DR   PANTHER; PTHR12815; PTHR12815; 1.
DR   Pfam; PF01103; Omp85; 1.
DR   Pfam; PF07244; POTRA; 1.
DR   PROSITE; PS51779; POTRA; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome;
KW   Transmembrane; Transmembrane beta strand.
FT   CHAIN           1..468
FT                   /note="Sorting and assembly machinery component 50 homolog
FT                   B"
FT                   /id="PRO_0000383684"
FT   DOMAIN          44..124
FT                   /note="POTRA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   468 AA;  52039 MW;  E319E37132B02155 CRC64;
     MGTVHARSLD PLPMNGPDFG SPDDADLVEV EPEKKQEILE NKDVVVQRVH FEGLGRTKDD
     LIAHEIGQVF KAKNLIEVMR KSHEAREKLL RLGVFRNVEV LIDTSEGEDA VPNGLDVTFE
     VTELRRLTGS YNTMVGNNEG SMVLGLKFPN LFGRAEKMTF QFSYGTKETS YGLSFFKPQV
     GNFERNFSVN LYKVTGQFPW SSLRETDRGV SAEINFPIWK TSHTLKWEGV WRELGCLART
     ASFAIREESG HTLKSSLSHT MVIDSRNASI LPKRGALLKI NQELAGYTGG DVSFLKEDFE
     LQLNKQLAWD SVLSTSLWGG MLVPVGDRPS SIADRFYLGG PTSVRGFSMY SIGPQSEGDY
     LGGEAYWAGG VHLYTPLPFR PGRGGFGDLF RTHFFLNAGN LCNLNYGEGP RAHLQRLAEC
     IRWSYGAGLV LRLGNIARLE LNYCIPMGVQ SGDRICDGVQ FGAGIRFL