SAMBA_ARATH
ID SAMBA_ARATH Reviewed; 100 AA.
AC Q9C613;
DT 05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Protein SAMBA {ECO:0000303|PubMed:22869741};
GN Name=SAMBA {ECO:0000303|PubMed:22869741};
GN OrderedLocusNames=At1g32310 {ECO:0000312|Araport:AT1G32310};
GN ORFNames=F27G20.14 {ECO:0000312|EMBL:AEE31462.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH CDC27B AND
RP CYCA2-3, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=22869741; DOI=10.1073/pnas.1211418109;
RA Eloy N.B., Gonzalez N., Van Leene J., Maleux K., Vanhaeren H., De Milde L.,
RA Dhondt S., Vercruysse L., Witters E., Mercier R., Cromer L., Beemster G.T.,
RA Remaut H., Van Montagu M.C., De Jaeger G., Ferreira P.C., Inze D.;
RT "SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is
RT involved in early development and A-type cyclin stabilization.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:13853-13858(2012).
CC -!- FUNCTION: Plays an important role in organ size control. Acts as
CC negative regulator of the anaphase-promoting complex/cyclosome (APC/C).
CC Regulates cell proliferation during early development by targeting
CC CYCA2-3 for APC/C-mediated degradation. Required for mitosis I during
CC pollen microspore development. {ECO:0000269|PubMed:22869741}.
CC -!- SUBUNIT: Interacts with CDC27B and CYCA2-3.
CC {ECO:0000269|PubMed:22869741}.
CC -!- TISSUE SPECIFICITY: Expressed in embryos, germinating seeds, hypocotyls
CC and pollen grains. {ECO:0000269|PubMed:22869741}.
CC -!- DISRUPTION PHENOTYPE: Growth-related phenotypes, such as formation of
CC large roots, leaves and seeds, enlarged meristem size, and reduced
CC fertility due to defect in male gametogenesis.
CC {ECO:0000269|PubMed:22869741}.
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DR EMBL; AC084110; AAG60169.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31462.1; -; Genomic_DNA.
DR EMBL; BT004179; AAO42198.1; -; mRNA.
DR EMBL; BT005704; AAO64124.1; -; mRNA.
DR EMBL; AY086534; AAM63599.1; -; mRNA.
DR RefSeq; NP_564394.1; NM_102964.5.
DR AlphaFoldDB; Q9C613; -.
DR SMR; Q9C613; -.
DR IntAct; Q9C613; 18.
DR STRING; 3702.AT1G32310.1; -.
DR PaxDb; Q9C613; -.
DR PRIDE; Q9C613; -.
DR ProteomicsDB; 232928; -.
DR EnsemblPlants; AT1G32310.1; AT1G32310.1; AT1G32310.
DR GeneID; 840123; -.
DR Gramene; AT1G32310.1; AT1G32310.1; AT1G32310.
DR KEGG; ath:AT1G32310; -.
DR Araport; AT1G32310; -.
DR TAIR; locus:2028296; AT1G32310.
DR eggNOG; ENOG502S622; Eukaryota.
DR HOGENOM; CLU_159573_1_0_1; -.
DR OMA; WMFEGPR; -.
DR OrthoDB; 1601644at2759; -.
DR PRO; PR:Q9C613; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C613; baseline and differential.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IDA:TAIR.
DR GO; GO:0009556; P:microsporogenesis; IMP:TAIR.
DR GO; GO:0046621; P:negative regulation of organ growth; IMP:TAIR.
DR GO; GO:0009555; P:pollen development; IMP:TAIR.
DR GO; GO:0045732; P:positive regulation of protein catabolic process; IMP:TAIR.
DR InterPro; IPR037547; SAMBA.
DR PANTHER; PTHR37387; PTHR37387; 1.
PE 1: Evidence at protein level;
KW Growth regulation; Reference proteome.
FT CHAIN 1..100
FT /note="Protein SAMBA"
FT /id="PRO_0000440870"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 100 AA; 10856 MW; 7B625223BF9CBCBB CRC64;
MNGASPAHSL VSTTAVAGGG GSSGAAAGLD DFHFPPDIPS MQERKDEAMR VLKADLMTEL
DKEVKSLEED SWMFEGPRSR IHLISRRGNF LKKGGEVKLW
