ID   SAMB_SALTM              Reviewed;         424 AA.
AC   P23832;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Protein SamB;
GN   Name=samB;
OS   Salmonella typhimurium.
OG   Plasmid 60-MDa cryptic.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90371;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 29631 / TA 1538;
RX   PubMed=1991707; DOI=10.1128/jb.173.3.1051-1063.1991;
RA   Nohmi T., Hakura A., Nakai Y., Watanabe M., Murayama S.Y., Sofuni T.;
RT   "Salmonella typhimurium has two homologous but different umuDC operons:
RT   cloning of a new umuDC-like operon (samAB) present in a 60-megadalton
RT   cryptic plasmid of S. typhimurium.";
RL   J. Bacteriol. 173:1051-1063(1991).
CC   -!- FUNCTION: Involved in UV protection and mutation.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-Y family. {ECO:0000305}.
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DR   EMBL; D90202; BAA14226.1; -; Genomic_DNA.
DR   PIR; B38176; B38176.
DR   AlphaFoldDB; P23832; -.
DR   SMR; P23832; -.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1490.100; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR   InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR   InterPro; IPR025188; DUF4113.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   Pfam; PF13438; DUF4113; 1.
DR   Pfam; PF00817; IMS; 1.
DR   Pfam; PF11799; IMS_C; 1.
DR   SUPFAM; SSF100879; SSF100879; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
DR   PROSITE; PS50173; UMUC; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Plasmid; SOS mutagenesis; SOS response.
FT   CHAIN           1..424
FT                   /note="Protein SamB"
FT                   /id="PRO_0000173981"
FT   DOMAIN          2..189
FT                   /note="UmuC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00216"
SQ   SEQUENCE   424 AA;  47727 MW;  FF8C47476CC58A2B CRC64;
     MFALADVNSF YASCEKVFRP DLRDRSVVVL SNNDGCVIPR SAEAKKLGIK MGVPWFQLRS
     AKFPEPVIAF SSNYALYASM SNRVMVHLEE LAPRVEQYSI DEMFLDIRGI DSCIDFEDFG
     RQLREHVRSG TGLTIGVGMG PTKTLAKSAQ WASKEWSQFG GVLALTLHNQ KRTEKLLSLQ
     PVEEIWGVGR RISKKLNTMG ITTALQLARA NPTFIRKNFN VVLERTVREL NGESCISLEE
     APPPKQQIVC SRSFGERVTT YEAMRQAVCQ HAERAAEKLR GERQFCRHIA VFVKTSPFAV
     TEPYYGNLAS EKLLIPTQDT RDIIAAAVRA LDRIWVDGHR YAKAGCMLND FTPTGVSQLN
     LFDEVQPRER SEQLMQVLDG INHPGKGKIW FAGRGIAPEW QMKRELLSPA YTTRWADIPA
     AKLT