SAMP_HIPHI
ID SAMP_HIPHI Reviewed; 29 AA.
AC P86695;
DT 10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT 10-AUG-2010, sequence version 1.
DT 25-MAY-2022, entry version 16.
DE RecName: Full=Serum amyloid P-component {ECO:0000250|UniProtKB:P02743};
DE AltName: Full=Agarose-binding protein {ECO:0000303|PubMed:9639088};
DE Short=Hh-ABP {ECO:0000303|PubMed:9639088};
DE Flags: Fragment;
OS Hippoglossus hippoglossus (Atlantic halibut) (Pleuronectes hippoglossus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Pleuronectidae;
OC Hippoglossus.
OX NCBI_TaxID=8267;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, COFACTOR, SUBUNIT, AND SUBCELLULAR LOCATION.
RC TISSUE=Serum {ECO:0000269|PubMed:9639088};
RX PubMed=9639088; DOI=10.1016/s0145-305x(97)00051-7;
RA Lund V., Olafsen J.A.;
RT "A comparative study of pentraxin-like proteins in different fish
RT species.";
RL Dev. Comp. Immunol. 22:185-194(1998).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000250|UniProtKB:P02743, ECO:0000269|PubMed:9639088};
CC Note=Binds 2 calcium ions per subunit. {ECO:0000250|UniProtKB:P02743,
CC ECO:0000269|PubMed:9639088};
CC -!- SUBUNIT: Homopentamer. Pentraxin (or pentaxin) have a discoid
CC arrangement of 5 non-covalently bound subunits.
CC {ECO:0000250|UniProtKB:P02743, ECO:0000269|PubMed:9639088}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:9639088}.
CC -!- SIMILARITY: Belongs to the pentraxin family. {ECO:0000255}.
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DR AlphaFoldDB; P86695; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR001759; Pentraxin-related.
DR PROSITE; PS51828; PTX_2; 1.
PE 1: Evidence at protein level;
KW Amyloid; Calcium; Direct protein sequencing; Lectin; Metal-binding;
KW Secreted.
FT CHAIN 1..>29
FT /note="Serum amyloid P-component"
FT /id="PRO_0000397213"
FT DOMAIN 6..>29
FT /note="Pentraxin (PTX)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01172"
FT UNSURE 1
FT /evidence="ECO:0000269|PubMed:9639088"
FT UNSURE 19
FT /evidence="ECO:0000269|PubMed:9639088"
FT NON_TER 29
FT /evidence="ECO:0000303|PubMed:9639088"
SQ SEQUENCE 29 AA; 3262 MW; B6B7CBF676F981D9 CRC64;
EPIDLLGKVF VFSKESNVDD VKLLTPQTE