SANT_PLAFP
ID SANT_PLAFP Reviewed; 76 AA.
AC P13822;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 1.
DT 25-MAY-2022, entry version 51.
DE RecName: Full=S-antigen protein;
DE Flags: Fragment;
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3278225; DOI=10.1016/0166-6851(88)90036-9;
RA Mattei D., Langsley G., Braun-Breton C., Guillotte M., Dubremetz J.-F.,
RA Mercereau-Puijalon O.;
RT "The S-antigen of Plasmodium falciparum Palo Alto represents a new S-
RT antigen serotype.";
RL Mol. Biochem. Parasitol. 27:171-180(1988).
CC -!- FUNCTION: S antigens are soluble heat-stable proteins present in the
CC sera of some infected individuals. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Parasitophorous vacuole
CC {ECO:0000250|UniProtKB:P04927}. Note=Localizes to the cell periphery in
CC early schizonts and then to the parasitophorous vacuole in late
CC schizonts. Following schizont rupture, the S-antigen is released in
CC host sera. {ECO:0000250|UniProtKB:P04927}.
CC -!- POLYMORPHISM: Diversity in S-antigen is mainly due to polymorphism in
CC the repetitive regions. {ECO:0000305|PubMed:3278225}.
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DR EMBL; M18834; AAA29759.1; -; Genomic_DNA.
DR PIR; A54499; A54499.
DR AlphaFoldDB; P13822; -.
DR GO; GO:0020003; C:symbiont-containing vacuole; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Malaria; Repeat.
FT CHAIN <1..>76
FT /note="S-antigen protein"
FT /id="PRO_0000217193"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT NON_TER 76
SQ SEQUENCE 76 AA; 7579 MW; ED5A931162449ACE CRC64;
EFRPNSDGDK GPNSDGDKGP NSDGDKGPNS DGDKGPNSDG DKGPNSDGDK GPNSDGDKGP
NSDGDKGPNS DGDTEF