SAP12_ARATH
ID SAP12_ARATH Reviewed; 186 AA.
AC Q67YE6; Q9XH76;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Zinc finger AN1 domain-containing stress-associated protein 12;
DE Short=AtSAP12;
GN Name=SAP12; Synonyms=PMZ; OrderedLocusNames=At3g28210; ORFNames=T19D11.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RA Jensen R.B., Skriver K., Jespersen H.M.;
RT "PMZ, a cDNA from Arabidopsis thaliana encoding a putative, novel zinc
RT finger motif with homologs in invertebrates and mammals.";
RL Plant Mol. Biol. 40:745-745(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY.
RX PubMed=17033811; DOI=10.1007/s00438-006-0165-1;
RA Vij S., Tyagi A.K.;
RT "Genome-wide analysis of the stress associated protein (SAP) gene family
RT containing A20/AN1 zinc-finger(s) in rice and their phylogenetic
RT relationship with Arabidopsis.";
RL Mol. Genet. Genomics 276:565-575(2006).
CC -!- FUNCTION: May be involved in environmental stress response.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q67YE6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q67YE6-2; Sequence=VSP_022105, VSP_022106;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD44285.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
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DR EMBL; AF139098; AAD37511.1; -; mRNA.
DR EMBL; AP002056; BAB02638.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77416.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65079.1; -; Genomic_DNA.
DR EMBL; BT024832; ABD60715.1; -; mRNA.
DR EMBL; AK176522; BAD44285.1; ALT_SEQ; mRNA.
DR EMBL; AK176745; BAD44508.1; -; mRNA.
DR PIR; T50672; T50672.
DR RefSeq; NP_001327074.1; NM_001338949.1. [Q67YE6-1]
DR RefSeq; NP_189461.1; NM_113740.6. [Q67YE6-1]
DR AlphaFoldDB; Q67YE6; -.
DR SMR; Q67YE6; -.
DR STRING; 3702.AT3G28210.1; -.
DR PaxDb; Q67YE6; -.
DR PRIDE; Q67YE6; -.
DR ProteomicsDB; 226588; -. [Q67YE6-1]
DR EnsemblPlants; AT3G28210.1; AT3G28210.1; AT3G28210. [Q67YE6-1]
DR EnsemblPlants; AT3G28210.2; AT3G28210.2; AT3G28210. [Q67YE6-1]
DR GeneID; 822447; -.
DR Gramene; AT3G28210.1; AT3G28210.1; AT3G28210. [Q67YE6-1]
DR Gramene; AT3G28210.2; AT3G28210.2; AT3G28210. [Q67YE6-1]
DR KEGG; ath:AT3G28210; -.
DR Araport; AT3G28210; -.
DR TAIR; locus:2098313; AT3G28210.
DR eggNOG; KOG3183; Eukaryota.
DR HOGENOM; CLU_061621_1_1_1; -.
DR InParanoid; Q67YE6; -.
DR OMA; GCRRKEM; -.
DR PhylomeDB; Q67YE6; -.
DR PRO; PR:Q67YE6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q67YE6; baseline and differential.
DR Genevisible; Q67YE6; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR Gene3D; 4.10.1110.10; -; 2.
DR InterPro; IPR035896; AN1-like_Znf.
DR InterPro; IPR000058; Znf_AN1.
DR Pfam; PF01428; zf-AN1; 2.
DR SMART; SM00154; ZnF_AN1; 2.
DR SUPFAM; SSF118310; SSF118310; 2.
DR PROSITE; PS51039; ZF_AN1; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Metal-binding; Reference proteome; Repeat; Zinc;
KW Zinc-finger.
FT CHAIN 1..186
FT /note="Zinc finger AN1 domain-containing stress-associated
FT protein 12"
FT /id="PRO_0000269863"
FT ZN_FING 10..58
FT /note="AN1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT ZN_FING 97..147
FT /note="AN1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT REGION 167..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 16
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 21
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 31
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 34
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 39
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 42
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 48
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 50
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 103
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 108
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 120
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 123
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 128
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 131
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 137
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 139
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT VAR_SEQ 38..50
FT /note="FCLEHRSYKSHNC -> RAFSQKLSIFFYN (in isoform 2)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_022105"
FT VAR_SEQ 51..186
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_022106"
SQ SEQUENCE 186 AA; 20665 MW; D16FE997CF35A857 CRC64;
MAGGGTEAFP DLGEHCQDPD CKLLDFLPFT CDGCKLVFCL EHRSYKSHNC PKSDHGSRTV
SICETCSIAI ETTGFDEKGI KSLLEKHERS GDCDPNKKKK PTCPVKRCKE ILTFANNLTC
KYCGVKFCLK HRFPTDHVCN KKIINTAGTS SRWNERFMEA LSLRNQKGCG RGSSVSSKSS
PSVRSF
