SAP2_ARATH
ID SAP2_ARATH Reviewed; 173 AA.
AC Q8H0X0; Q9SYC3;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Zinc finger A20 and AN1 domain-containing stress-associated protein 2;
DE Short=AtSAP2;
GN Name=SAP2; OrderedLocusNames=At1g51200; ORFNames=F11M15.6, F11M15.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=17033811; DOI=10.1007/s00438-006-0165-1;
RA Vij S., Tyagi A.K.;
RT "Genome-wide analysis of the stress associated protein (SAP) gene family
RT containing A20/AN1 zinc-finger(s) in rice and their phylogenetic
RT relationship with Arabidopsis.";
RL Mol. Genet. Genomics 276:565-575(2006).
CC -!- FUNCTION: May be involved in environmental stress response.
CC {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC006085; AAD30634.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32633.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32634.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32635.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32636.1; -; Genomic_DNA.
DR EMBL; AY056445; AAL08301.1; -; mRNA.
DR EMBL; BT001984; AAN71995.1; -; mRNA.
DR EMBL; BT015115; AAT71987.1; -; mRNA.
DR PIR; G96549; G96549.
DR RefSeq; NP_001077694.1; NM_001084225.2.
DR RefSeq; NP_001185193.1; NM_001198264.1.
DR RefSeq; NP_001185194.1; NM_001198265.1.
DR RefSeq; NP_564585.1; NM_103998.3.
DR AlphaFoldDB; Q8H0X0; -.
DR SMR; Q8H0X0; -.
DR BioGRID; 26768; 4.
DR IntAct; Q8H0X0; 4.
DR STRING; 3702.AT1G51200.3; -.
DR PaxDb; Q8H0X0; -.
DR PRIDE; Q8H0X0; -.
DR ProteomicsDB; 232867; -.
DR EnsemblPlants; AT1G51200.1; AT1G51200.1; AT1G51200.
DR EnsemblPlants; AT1G51200.2; AT1G51200.2; AT1G51200.
DR EnsemblPlants; AT1G51200.3; AT1G51200.3; AT1G51200.
DR EnsemblPlants; AT1G51200.4; AT1G51200.4; AT1G51200.
DR GeneID; 841543; -.
DR Gramene; AT1G51200.1; AT1G51200.1; AT1G51200.
DR Gramene; AT1G51200.2; AT1G51200.2; AT1G51200.
DR Gramene; AT1G51200.3; AT1G51200.3; AT1G51200.
DR Gramene; AT1G51200.4; AT1G51200.4; AT1G51200.
DR KEGG; ath:AT1G51200; -.
DR Araport; AT1G51200; -.
DR TAIR; locus:2008251; AT1G51200.
DR eggNOG; KOG3173; Eukaryota.
DR HOGENOM; CLU_057016_5_0_1; -.
DR OMA; PFDYHSA; -.
DR OrthoDB; 1551371at2759; -.
DR PhylomeDB; Q8H0X0; -.
DR PRO; PR:Q8H0X0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8H0X0; baseline and differential.
DR Genevisible; Q8H0X0; AT.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 4.10.1110.10; -; 1.
DR InterPro; IPR035896; AN1-like_Znf.
DR InterPro; IPR002653; Znf_A20.
DR InterPro; IPR000058; Znf_AN1.
DR Pfam; PF01754; zf-A20; 1.
DR Pfam; PF01428; zf-AN1; 1.
DR SMART; SM00259; ZnF_A20; 1.
DR SMART; SM00154; ZnF_AN1; 1.
DR SUPFAM; SSF118310; SSF118310; 1.
DR PROSITE; PS51036; ZF_A20; 1.
DR PROSITE; PS51039; ZF_AN1; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..173
FT /note="Zinc finger A20 and AN1 domain-containing stress-
FT associated protein 2"
FT /id="PRO_0000269855"
FT ZN_FING 12..46
FT /note="A20-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT ZN_FING 108..154
FT /note="AN1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 18
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 22
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 34
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 37
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 114
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 117
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 128
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 130
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 135
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 138
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 144
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 146
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT CONFLICT 49
FT /note="A -> T (in Ref. 3; AAN71995)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 173 AA; 18429 MW; 6A8F86CA09B3CBED CRC64;
MDHDKTGCQS PPEGPKLCTN NCGFFGSAAT MNMCSKCHKD MLFQQEQGAK FASAVSGTSS
SSNIIKETFT AALVDIETKS VEPMTVSVQP SSVQVVAEVV APEEAAKPKG PSRCTTCNKR
VGLTGFKCRC GSLFCGTHRY ADVHDCSFNY HAAAQEAIAK ANPVVKAEKL DKI
