SAP4_ARATH
ID SAP4_ARATH Reviewed; 161 AA.
AC Q9SJM6; Q0IGN9;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Zinc finger A20 and AN1 domain-containing stress-associated protein 4;
DE Short=AtSAP4;
GN Name=SAP4; OrderedLocusNames=At2g36320; ORFNames=F2H17.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=17033811; DOI=10.1007/s00438-006-0165-1;
RA Vij S., Tyagi A.K.;
RT "Genome-wide analysis of the stress associated protein (SAP) gene family
RT containing A20/AN1 zinc-finger(s) in rice and their phylogenetic
RT relationship with Arabidopsis.";
RL Mol. Genet. Genomics 276:565-575(2006).
RN [6]
RP STRUCTURE BY NMR OF 92-142.
RG RIKEN structural genomics initiative (RSGI);
RT "Solution structure of the ZF-AN1 domain from Arabidopsis thaliana
RT At2g36320 protein.";
RL Submitted (NOV-2004) to the PDB data bank.
CC -!- FUNCTION: May be involved in environmental stress response.
CC {ECO:0000250}.
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DR EMBL; AC006921; AAD21434.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09232.1; -; Genomic_DNA.
DR EMBL; BT028881; ABI49428.1; -; mRNA.
DR EMBL; AY086347; AAM64415.1; -; mRNA.
DR PIR; C84779; C84779.
DR RefSeq; NP_565844.1; NM_129189.5.
DR PDB; 1WFH; NMR; -; A=92-142.
DR PDBsum; 1WFH; -.
DR AlphaFoldDB; Q9SJM6; -.
DR SMR; Q9SJM6; -.
DR STRING; 3702.AT2G36320.1; -.
DR PaxDb; Q9SJM6; -.
DR PRIDE; Q9SJM6; -.
DR ProteomicsDB; 232685; -.
DR EnsemblPlants; AT2G36320.1; AT2G36320.1; AT2G36320.
DR GeneID; 818205; -.
DR Gramene; AT2G36320.1; AT2G36320.1; AT2G36320.
DR KEGG; ath:AT2G36320; -.
DR Araport; AT2G36320; -.
DR TAIR; locus:2049505; AT2G36320.
DR eggNOG; KOG3173; Eukaryota.
DR HOGENOM; CLU_057016_5_3_1; -.
DR InParanoid; Q9SJM6; -.
DR OMA; NDAFIFH; -.
DR OrthoDB; 1551371at2759; -.
DR PhylomeDB; Q9SJM6; -.
DR EvolutionaryTrace; Q9SJM6; -.
DR PRO; PR:Q9SJM6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJM6; baseline and differential.
DR Genevisible; Q9SJM6; AT.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 4.10.1110.10; -; 1.
DR InterPro; IPR035896; AN1-like_Znf.
DR InterPro; IPR002653; Znf_A20.
DR InterPro; IPR000058; Znf_AN1.
DR Pfam; PF01754; zf-A20; 1.
DR Pfam; PF01428; zf-AN1; 1.
DR SMART; SM00259; ZnF_A20; 1.
DR SMART; SM00154; ZnF_AN1; 1.
DR SUPFAM; SSF118310; SSF118310; 1.
DR PROSITE; PS51036; ZF_A20; 1.
DR PROSITE; PS51039; ZF_AN1; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..161
FT /note="Zinc finger A20 and AN1 domain-containing stress-
FT associated protein 4"
FT /id="PRO_0000066578"
FT ZN_FING 10..44
FT /note="A20-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT ZN_FING 96..142
FT /note="AN1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT REGION 76..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 16
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 20
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 32
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 35
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT BINDING 102
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 105
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 116
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 118
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 123
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 126
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 132
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT BINDING 134
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT TURN 103..105
FT /evidence="ECO:0007829|PDB:1WFH"
FT STRAND 117..119
FT /evidence="ECO:0007829|PDB:1WFH"
FT TURN 124..126
FT /evidence="ECO:0007829|PDB:1WFH"
FT TURN 129..133
FT /evidence="ECO:0007829|PDB:1WFH"
SQ SEQUENCE 161 AA; 17784 MW; BDF9CB123894DD95 CRC64;
MAEEHRCETP EGHRLCVNNC GFFGSSATMN LCSNCYGDLC LKQQQQASMK STVESSLSPV
IAPVLENYAA ELEIPTTKKT EEKKPIQIPT EQPSPPQRPN RCTVCRKRVG LTGFMCRCGT
TFCGSHRYPE VHGCTFDFKS AGREEIAKAN PLVIAAKLQK I
