ID   SAPA_HAEIN              Reviewed;         565 AA.
AC   P45285;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Peptide transport periplasmic protein SapA;
DE   Flags: Precursor;
GN   Name=sapA; OrderedLocusNames=HI_1638;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in a peptide intake transport system that plays a
CC       role in the resistance to antimicrobial peptides. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC23285.1; -; Genomic_DNA.
DR   PIR; A64134; A64134.
DR   RefSeq; NP_439780.1; NC_000907.1.
DR   RefSeq; WP_005693646.1; NC_000907.1.
DR   AlphaFoldDB; P45285; -.
DR   SMR; P45285; -.
DR   STRING; 71421.HI_1638; -.
DR   EnsemblBacteria; AAC23285; AAC23285; HI_1638.
DR   KEGG; hin:HI_1638; -.
DR   PATRIC; fig|71421.8.peg.1714; -.
DR   eggNOG; COG4166; Bacteria.
DR   HOGENOM; CLU_017028_7_0_6; -.
DR   OMA; NQYVRLV; -.
DR   PhylomeDB; P45285; -.
DR   BioCyc; HINF71421:G1GJ1-1655-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR   GO; GO:1904680; F:peptide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015833; P:peptide transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR023765; SBP_5_CS.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
DR   PROSITE; PS01040; SBP_BACTERIAL_5; 1.
PE   3: Inferred from homology;
KW   Peptide transport; Periplasm; Protein transport; Reference proteome;
KW   Signal; Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..565
FT                   /note="Peptide transport periplasmic protein SapA"
FT                   /id="PRO_0000031803"
SQ   SEQUENCE   565 AA;  64504 MW;  449E454F1278C2A7 CRC64;
     MLRLNLRFLS FLLCIIQSVE LQAAPSVPTF LTENGLTYCT HASGFSFNPQ TADAGTSMNV
     VTEQIYNKLF DIKNHSATLT PMLAQSYSIS ADGKEILLNL RHGVKFHQTP WFTPTRDFNA
     EDVVFSINRV LGGHNTYLPT LAETNVTYSN PQYRVFHEQA RKVRFPYFDS IKLNEKIKSV
     TALSPYQVKI ELFAPDSSIL SHLASQYAII FSQEYAYQLS ADDNLAQLDT HPVGTGPYQV
     KDYVYNQYVR LVRNENYWKK EAKIEHIIVD LSTDRSGRLV KFFNNECQIA SYPEVSQIGL
     LKNDDKHYYM QSTDGMNLAY LAFNFDKPLM RDHEIRAAIS QSLNRARIIH SIYHNTATVA
     NNIIPEVSWA SSVNTPEFEF DYNPKIAKNK LADKNLLLNL WVINEEQVYN PAPFKIAEMI
     KWDLAQAGVK VKVRAVTRPF LTAQLRNQSE NYDLILSGWL AGNLDPDGFM RPILSCGTKN
     ELTNLSNWCN EEFDQFMDRA ITTSHLSSRA KAYNEAQELV LRELPIIPIA NVKRILVANS
     RVKGVKMTPF GSLDFSTLYF IQEKY