SAPC1_MOUSE
ID SAPC1_MOUSE Reviewed; 146 AA.
AC Q9CY86; B2RWH1; Q9Z1Q7;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Suppressor APC domain-containing protein 1;
DE AltName: Full=Protein G7d;
GN Name=Sapcd1; Synonyms=G7d, Ng23;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=C57BL/10;
RX PubMed=11797099; DOI=10.1007/s00251-001-0381-0;
RA van Kooij M., de Groot K., van Vugt H., Aten J., Snoek M.;
RT "Genotype versus phenotype: conflicting results in mapping a lung tumor
RT susceptibility locus to the G7c recombination interval in the mouse MHC
RT class III region.";
RL Immunogenetics 53:656-661(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=129;
RX PubMed=14656967; DOI=10.1101/gr.1736803;
RA Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D.,
RA Hood L.;
RT "Analysis of the gene-dense major histocompatibility complex class III
RT region and its comparison to mouse.";
RL Genome Res. 13:2621-2636(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AF397035; AAL14455.1; -; Genomic_DNA.
DR EMBL; AF397036; AAL14463.1; -; Genomic_DNA.
DR EMBL; AF109905; AAC84153.1; -; Genomic_DNA.
DR EMBL; AK019275; BAB31642.1; -; mRNA.
DR EMBL; BC147772; AAI47773.1; -; mRNA.
DR EMBL; BC147780; AAI47781.1; -; mRNA.
DR CCDS; CCDS37594.1; -.
DR RefSeq; NP_076382.3; NM_023893.4.
DR AlphaFoldDB; Q9CY86; -.
DR SMR; Q9CY86; -.
DR STRING; 10090.ENSMUSP00000047448; -.
DR PhosphoSitePlus; Q9CY86; -.
DR PaxDb; Q9CY86; -.
DR PRIDE; Q9CY86; -.
DR Antibodypedia; 70925; 23 antibodies from 9 providers.
DR Ensembl; ENSMUST00000040151; ENSMUSP00000047448; ENSMUSG00000036185.
DR GeneID; 78376; -.
DR KEGG; mmu:78376; -.
DR UCSC; uc008cfb.3; mouse.
DR CTD; 401251; -.
DR MGI; MGI:2388100; Sapcd1.
DR VEuPathDB; HostDB:ENSMUSG00000036185; -.
DR eggNOG; ENOG502SES6; Eukaryota.
DR GeneTree; ENSGT00500000045192; -.
DR HOGENOM; CLU_129376_0_0_1; -.
DR InParanoid; Q9CY86; -.
DR OMA; RQDALWQ; -.
DR OrthoDB; 1404978at2759; -.
DR PhylomeDB; Q9CY86; -.
DR TreeFam; TF324086; -.
DR BioGRID-ORCS; 78376; 6 hits in 73 CRISPR screens.
DR PRO; PR:Q9CY86; -.
DR Proteomes; UP000000589; Chromosome 17.
DR RNAct; Q9CY86; protein.
DR Bgee; ENSMUSG00000036185; Expressed in epithelium of lens and 90 other tissues.
DR ExpressionAtlas; Q9CY86; baseline and differential.
DR Genevisible; Q9CY86; MM.
DR InterPro; IPR026828; Suppressor_APCD_1/2.
DR PANTHER; PTHR14907; PTHR14907; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..146
FT /note="Suppressor APC domain-containing protein 1"
FT /id="PRO_0000244083"
FT REGION 121..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 94
FT /note="E -> Q (in Ref. 3; BAB31642)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 146 AA; 16181 MW; 1DBBF079F8DC2FFF CRC64;
MESPGPGGPP LVQAPYTVLL LPLGTSRQDP GAQNFFLWLQ MMQALEREQD ALWQGLELLE
HGQAWFADRL RETQQRQLQL GALGEDFLMD LHSETDAPLL TRIQKVNACL HSLIHKELSK
HRKGVTQSTG EVVSQAPPGP KGPTLV
