ID   SAP_STOVA               Reviewed;           9 AA.
AC   P24047;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   11-DEC-2019, entry version 33.
DE   RecName: Full=Sperm-activating peptide;
DE            Short=SAP;
OS   Stomopneutes variolaris (Sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Acroechinoidea; Diadematacea; Phymosomatoida; Stomechinidae;
OC   Stomopneustes.
OX   NCBI_TaxID=7663;
RN   [1]
RP   PROTEIN SEQUENCE, AND DISULFIDE BOND.
RC   TISSUE=Egg jelly;
RX   PubMed=1756858; DOI=10.1016/0014-5793(91)80663-n;
RA   Yoshino K., Takao T., Shimonishi Y., Suzuki N.;
RT   "Determination of the amino acid sequence of an intramolecular disulfide
RT   linkage-containing sperm-activating peptide by tandem mass spectrometry.";
RL   FEBS Lett. 294:179-182(1991).
CC   -!- FUNCTION: Causes stimulation of sperm respiration and motility through
CC       intracellular alkalinization, transient elevations of cAMP, cGMP and
CC       calcium levels in sperm cells, and transient activation and subsequent
CC       inactivation of the membrane form of guanylate cyclase.
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PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond.
FT   PEPTIDE         1..9
FT                   /note="Sperm-activating peptide"
FT                   /id="PRO_0000044217"
FT   DISULFID        3..8
FT                   /evidence="ECO:0000269|PubMed:1756858"
SQ   SEQUENCE   9 AA;  1010 MW;  C469B3387B076EB9 CRC64;
     KFCPEGKCV