SAR2_SOLLC
ID SAR2_SOLLC Reviewed; 193 AA.
AC P52884;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=GTP-binding protein SAR2;
GN Name=SAR2;
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Pericarp;
RX PubMed=8123794; DOI=10.1007/bf00024120;
RA Davies C.;
RT "Cloning and characterization of a tomato GTPase-like gene related to yeast
RT and Arabidopsis genes involved in vesicular transport.";
RL Plant Mol. Biol. 24:525-531(1994).
CC -!- FUNCTION: Involved in transport from the endoplasmic reticulum to the
CC Golgi apparatus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250}. Golgi
CC apparatus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. SAR1 family.
CC {ECO:0000305}.
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DR EMBL; L12051; AAA34168.1; -; mRNA.
DR PIR; S42528; S42528.
DR RefSeq; NP_001234640.1; NM_001247711.1.
DR AlphaFoldDB; P52884; -.
DR SMR; P52884; -.
DR STRING; 4081.Solyc01g060130.2.1; -.
DR PaxDb; P52884; -.
DR PRIDE; P52884; -.
DR EnsemblPlants; Solyc01g060130.3.1; Solyc01g060130.3.1; Solyc01g060130.3.
DR GeneID; 543958; -.
DR Gramene; Solyc01g060130.3.1; Solyc01g060130.3.1; Solyc01g060130.3.
DR KEGG; sly:543958; -.
DR eggNOG; KOG0077; Eukaryota.
DR HOGENOM; CLU_040729_6_0_1; -.
DR InParanoid; P52884; -.
DR OMA; YGQTTRK; -.
DR OrthoDB; 1168548at2759; -.
DR PhylomeDB; P52884; -.
DR Proteomes; UP000004994; Chromosome 1.
DR GO; GO:0030127; C:COPII vesicle coat; IBA:GO_Central.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0061024; P:membrane organization; IBA:GO_Central.
DR GO; GO:0070863; P:positive regulation of protein exit from endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0003400; P:regulation of COPII vesicle coating; IBA:GO_Central.
DR GO; GO:0016050; P:vesicle organization; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR006687; Small_GTPase_SAR1.
DR PANTHER; PTHR45684; PTHR45684; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51422; SAR1; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; GTP-binding;
KW Nucleotide-binding; Protein transport; Reference proteome; Transport.
FT CHAIN 1..193
FT /note="GTP-binding protein SAR2"
FT /id="PRO_0000206269"
FT BINDING 27..34
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 70..73
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 129..132
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
SQ SEQUENCE 193 AA; 21923 MW; CF5223DB9DE99B4F CRC64;
MFLVDWFYGV LASLGLWQKD AKILFLGLDN AGKTTLLHML KDERLVQHQP TQYPTSEELS
IGNIKFKAFD LGGHQIARRV WRDYYAKVDA VVYLVDANDR ERFPEAKKEL DGLLSDESLT
NVPFLILGNK IDIPYAASED ELRYHLGLTG VTTGKGNINL AGTNVRPIEV FMCSIVRKMG
YGEGFKWMSQ YIK
